8 documents found, page 1 of 1
Exposição ocupacional dos agentes de combate as endemias aos inseticidas
Costa, Josiane Maria Soares da; Barbosa, Maria Lucianny Lima; Silveira, Helson Freitas da; Ferreira, Tereza Maria da Silva; Oliveira, Thompson Lopes dePesticides are chemical compounds known for their neurotoxic properties, often held responsible for the poisoning of workers who handle and apply pesticides. Can be classified as: herbicides, fungicides and insecticides. Occupational exposure to pesticides in Brazil is a public health problem, which remains underreported, making it difficult for public policy practices for prevention of pesticide poisoning. The...
Toxicogenetic profile of rats treated with aqueous extract from Morinda citrifo...
Moraes, Germano Pinho de; Alencar, Marcus Vinícius Oliveira Barros de; Islam, Torequl; Araújo, Lidiane da Silva; Gomes, Débora Cássia VieiraMorinda citrifolia ( (Family: Rubiaceae) ) is extensive ly use d in traditional med icine due to its anti - inflammatory, antimicrobial, antitumoral , and anti - hypertensive act ivities . However, t here is no substantial data about hepatotoxic and toxicogenetic effects . This study evaluated bioch emical changes and hepatotoxic, genotoxic , and mu tagenic effects of aqueous extract of the fruit of M. citrifol...
Preparation of phytol-loaded nanoemulsion and screening for antioxidant capacity
Islam, Torequl; Streck, Leticia; Paz, Márcia Fernanda Correia Jardim; Sousa, João Marcelo de Castro e; Alencar, Marcus Vinícius Oliveira Barros deThe study prepared a nanoemulsion with a diterpenoid isoprenoid alcohol called phytol (PYT) and subsequently tested it for antioxidant capacity. For this, PYT-loaded nanoemulsion was prepared by phase inversion method and both PYT-containing nanoemulsion (PNE) and PYT-free nanoemulsion (PFNE) (2-16 µM) were tested for antiradical activity (DPPH•: 1,1-dipheny-picrylhydrazyl radical; ABTS•+: azino-bisethylbenzthi...
Cytogenotoxic and oxidative status evaluation of Morinda citrifolia
Moraes, Germano Pinho de; Alencar, Marcus Vinícius Oliveira Barros de; Islam, Torequl; Araújo, Lidiane da Silva; Sobral, André Luiz PinhoCancer is one of the most leading causes of death worldwide. Morinda citrifolia was reported to have antitumor effects. Cisplatin (CDDP), Doxorubicin (DOX) and Cyclophosphamid (CPA) are the known effective chemotherapeutics, despite of having several side effects. This study evaluated antitumoral and oxidative effects of the aqueous extract of the fruit of M. critrifolia (AEMC) (15, 30, 60 and 120 µg/mL) in com...
Genotoxicity and DNA repair indicative in blood cells after occupational exposu...
Silva, Ronald Gerard; Alencar, Marcus Vinícius Oliveira Barros de; Teixeira, Jadson Silva T; Silva, Reyca Rodrigues eOccupational exposure to ionizing radiation (IR) can damage DNA. The study evaluated the genotoxic profile and repair indicatives of DNA from peripheral blood lymphocytes of health workers exposed occupationally to IR by adopting comet assay. Biomonitoring was done with ninety individuals; among them 45 were health professionals and the rests were non-professionals. Blood samples were collected after 48 h (2 d;...
Evaluation of antioxidant capacity of the aqueous extract of Cynara scolymus L....
Oliveira, George Laylson da Silva; Oliveira, Francisco Rodrigo de Asevedo Mendes de; Alencar, Marcus Vinícius Oliveira Barros deThe present study evaluated the antioxidant capacity of the aqueous extract of the leaves of Cynara scolymus on Saccharomyces cerevisiae strains, proficient and deficient in antioxidant defenses, and by in vitro methods with 1,1-diphenyl-2-picrylhydrazyl (DPPH•), 2,2'-azinobis-3-ethylbenzothiazoline-6- sulfonic acid (ABTS•+), inhibition of hydrogen peroxide, lipid peroxidation, formation of nitric oxide, and re...
Prospecção tecnológica : utilização de alcaloides no tratamento da doença de al...
Oliveira, Francisco Rodrigo de Asevedo Mendes de; Oliveira, George Laylson da Silva; Oliveira, Johanssy da SilvaAlzheimer's disease (AD) is a neurological disorder that affects more people around the world. Currently, natural compounds derived from plants such as alkaloids, may be a promising alternative, effective and with fewer side effects for the development of drugs for AD. The aim of this study was to perform a technological forecasting alkaloids for the treatment of AD, analyzing the amount of records deposits pat...
Relação entre consumo alimentar da população nordestina e o alto índice de cânc...
Oliveira, Victor Alves de; Oliveira, Thayse Wilma Nogueira de; Alencar, Marcus Vinícius Oliveira Barros de; Cerqueira, Gilberto Santos; Peron, Ana PaulaWorldwide, stomach cancer appears as the second leading cause of cancer death. The relationship between gastric cancer and nutrition is suggested in several studies, the diet being a very important exogenous factor. Thus, this paper aims to cross data between dietary profile of the northeastern Brazilian population with studies that investigated the relationship between gastric cancer and the main food items co...