2 documents found, page 1 of 1
Associations of polymorphisms of folate cycle enzymes and risk of breast cancer...
Barbosa, Rita de Cássia Carvalho; Costa, Débora Menezes da; Freire, Thiago Fernando Vasconcelos; Sales, Diogo Campos; Alencar, Victor Hugo MedeirosPolymorphisms in genes involved in folate metabolism have been shown to be implicated in breast cancer risk but with contradictory results. In this case– control study, we investigated the association between MTHFR C677T and A1298C, TYMS 5 0 -UTR, MTR A2756G and c SHMT C1420T and also the folate carrier ( RFC1 G80A) and breast cancer risk in a northeastern Brazilian population. The study included 183 women diag...
Avaliação do tratamento adjuvante com tamoxifeno em mulheres com câncer de mama
Alencar, Victor Hugo MedeirosBreast cancer is a disease that was described many years ago and has been documented, for the first time, by Imhotep, physician, astrologer and Egyptian architect, born in 2.650 before Christ (b.C.), who recommended, at that time, as a way of treatment, cauterization of the diseased tissue. Tamoxifen is the drug more prescribed in the treatment of breast cancer. It’s use is mainly in the adjuvant modality, in p...