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GENETIC CHARACTERIZATION NATIVE CATTLE OF ANGOLA USING WHOLE GENOME SEQUENCING

Sebastino, K; Chiaia, H; Teixeira, F; Gaspar, J; Afonso, P; Cláudio, S; Nanga, P; Pires, J; Adelino, M; Ngola, S; Casimiro, J; Gomes, L; Dala, E

In Angola, about 70% of the population relies on subsistence agriculture, with cattle production crucial to the economy and culture of the southern regions. Local cattle breeds face extinction due to crossbreeding with improved breeds or replacement by exotic commercial breeds, risking the loss of unique genetic traits vital for adapting to Angola's ecosystems. This project aims to establish a biobank represent...


Uncovering the genetic diversity of native bovine from South Angola

Sebastino, K; Chiaia, H; Afonso, P; Gaspar, J; Teixeira, F; Ngola, S; Simão, C; Casimiro, J; Nanga, P; Miguel, A; Gomes, L; Alexandre, A; Leitão, A

cattle in Angola and how they relate to other breeds. In Africa we find Bos taurus and Bos indicus cattle and a hybrid also known as Sanga cattle. The most dominant cattle in Angola are Sanga which name varies according to the location and native language of the region, existing 11 different denominations, which conservation status in unknown. Sampling was performed between 2023 and 2024 in different provinces....


Ticagrelor Loading on ST-Elevation Myocardial Infarction: Interaction With Prod...

Faria, JP; Oliveira, P; Alexandre, A; Couto, DS; Costa, R; Campinas, A; Frias, A; Brochado, B; Santos, R; Silveira, J; Torres, S; Luz, A

Introduction:Ticagrelor might reduce infarct size by exerting a more potent antiplatelet effect or by promoting a potential conditioning stimulus in ST-elevation myocardial infarction (STEMI) patients. Pre-infarction angina (PIA) is an effective preconditioning stimulus that reduces ischemia-reperfusion injury. Because little is known on the interaction of PIA in STEMI-patients loaded with ticagrelor, we sought...


Genomic characteristics and comparative genomics analyses of non-rhizobial endo...

Torres, DP; Alexandre, A; Menendez, E; Brígido, C

In addition to typical nitrogen-fixing endosymbionts, legumes harbour other endophytic bacteria within their tissues that may also contribute to plant growth and health (Hardoim et al. 2015). Our previous works revealed that endophytic bacteria isolated from legumes not only have plant growth-promoting traits but are also well adapted to common constraints present in soils of the Mediterranean region (Brígido e...


Very Delayed Lupus Nephritis: a Report of Three Cases and Literature Review

Alexandre, A; Carreira, P; Isenberg, DA

Lupus nephritis (LN) affects up to 50% of patients with Systemic Lupus Erythematosus (SLE) and is associated with a worse prognosis. LN usually develops within the first 5 years of the onset of the disease. We report three patients with very delayed LN (DLN) diagnosed after 15 or more years after SLE diagnosis. The three patients were non-Caucasian women with adolescent or adult-onset SLE. Each had antinuclear,...


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