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Doença Articular em Equinos: Metodologias de Diagnóstico

Alexandre, Nuno; Branco, Sandra; Bettencourt, Elisa; Ramos, Sofia; Mendes, António; Cardoso, Madalena; Marques, João Paulo; Crespo, João

A doença articular é uma das causas mais frequentes de claudicação em equinos e, consequentemente, de diminuição da performance e retirada precoce da carreira desportiva. A terminologia “doença articular” é um termo muito abrangente, incluindo afeções articulares de causas traumáticas, degenerativas, inflamatórias e infecciosas. A avaliação de cada caso clínico implica não só um exame clínico minucioso, mas tam...


Prevalence of radiographic signs of osteoarthritis in Lusitano Purebred horses

Ramos, Sofia; Pinto, António; Cardoso, Madalena; Alexandre, Nuno; Bettencourt, Elisa; Monteiro, Susana; Telo Gama, Luis

Radiographic prevalence and correlation of radiographic findings has not been performed in Lusitano Purebred horses. The aim of this study was to (1) evaluate the prevalence of primary osteoarthritis radiographic findings in Lusitano Purebred horses; (2) to assess correlations between radiographic findings in different joints of the same limb and different limbs; and (3) elucidate the effect of age in the radio...


FELINE RENAL CHRONIC DISEASE: A RETROSPECTIVE STUDY OF THE SERUM CREATINE VALUE...

Rodrigues, Maria João; Oliveira, Ana; Alexandre, Nuno

Introduction Chronic kidney disease (CKD) is one the most prevalent medical conditions affecting geriatric cats. After CKD becomes clinical, periods of exacerbation and stability alternate, making it difficult to predict the next relapse. The objective of these study was to verify the existence of a correlation between creatininemia in cats with CKD at discharge and the period of relapse (days), providing the p...


Eyelid Reconstruction and Infraorbital Repair Using a Mustardé Flap Technique i...

Guerra Guimarães, Tarcísio; Menezes Cardoso, Karla; Pacheco, Magda; Olivério, Pedro; Faim, Susana; Marto, Carlos Miguel; Alexandre, Nuno

This case report describes a 5-year-old dog with a defect in the right eyelid, absence of orbicularis musculature, and absence of cutaneous tissue in the infraorbital region, submitted to the Mustardé flap technique. A large rotational flap was performed, including a cartilage graft from the outer ear, to correct the defect in the lower eyelid and infraorbital region. Also, euryblepharon correction of the upper...


Evaluation of eye melanoma treatments in rabbits: A systematic review.

Guimarâes, Tarcísio Guerra; Marto, Carlos Miguel; Cardoso, Karla Menezes; Alexandre, Nuno; Botelho, Maria Filomena; Laranjo, Mafalda

Guimarães, T. G., Marto, C. M., Cardoso, K. M., Alexandre, N., Botelho, M. F., & Laranjo, M. (2022). Evaluation of eye melanoma treatments in rabbits: A systematic review [Review]. Laboratory Animals, 56(2), 119-134. https://doi.org/10.1177/00236772211039333


OPHTHALMOLOGICAL EVALUATION OF SHEEP FROM THE ALENTEJO REGION -PORTUGAL

Guimarães, Tarcísio Guerra; Menezes Cardoso, Karla; Hadade, Ismail Ramalho; Marques Brito, Marta; Melo Oliveira, Manuela; Vilela Mamede, Fabricio

Considering the importance of the flock of Alentejo sheep, the goal of this study was to determine the average values of eye examinations, evaluate the ophthalmoscopic features and fluorescein staining for Merino sheep from Alentejo region, in Portugal. The 48 eyes of 24 healthy, female sheep belonging to the sheep flock at the University of Évora were evaluated. The average values obtained for Schirmer tear te...


Localização subcelular do novo fotossensibilizador em células do melanoma ocula...

Guimarães, Tarcísio Guerra; Menezes Cardoso, Karla; Marto, Carlos Miguel; Teixo, Ricardo; Serambeque, Beatriz; Pereira, Nélson; Piñeiro, Marta

Introdução: O melanoma ocular é o objetivo de várias investigações em medicina e medicina veterinária devido à baixa taxa de resposta aos tratamentos conservadores convencionais1. A terapia fotodinâmica (PDT) é uma terapia mais conservadora para os tecidos não neoplásicos, que induz e ativa as vias de morte celular nos tecidos neoplásicos alvo2,3. O fotossensibilizador, luz e oxigenio são os três componentes vi...


OCULAR MELANOMA IN DOGS AND CATS: EPIDEMIOLOGICAL SURVEY IN PORTUGA

Guimarães, Tarcísio Guerra; Mamede, Fábio; Cardoso, Karla Menezes; Marto, Carlos; Caramelo, Francisco; Tasso, Gláuber; Andrade, Arthur; Alexandre, Nuno

Purpose: The epidemiology of ocular melanoma in dogs and cats in Portugal was assessed. Methods: Data collection was carried out through the distribution of an online questionnaire for veterinarians in Portugal. The survey covered the year 2018 and was made available for responses from 2019-2020. Results: 47 responses were obtained, representing 5.7% of there turn to the survey. A total of 32.61% of the profess...


IN VITRO PHOTODYNAMIC THERAPY ON OCULAR MELANOMA CELLS

Guimarães, Tarcísio Guerra; Carvalho, Gabriela; Mamede, Fabrício Vilela; Cardoso, Karla Menezes; Marto, Carlos Miguel; Piñeiro, Marta

Purpose. To evaluate the effect of newly developed Ring-fused chlorins on cell proliferation of ocular melanoma. Methods. Human cell line MP-41 and a canine primary culture were subjected to the photosensitizers at concentrations between 0,5-1000 nM for 24 hours. The cells were irradiated with 10J (ƛ>570nm). Control groups included: untreated cells and cells submitted only to the administration vehicle (dimethy...


Manifestações oculares de doenças sistémicas.

Guimarães, Tarcísio; Cardoso, Karla; Botelho, Fátima; Laranjo, Mafalda; Alexandre, Nuno

Introdução A manifestação clínica ocular secundária a doenças sistêmicas é comum em diversas espécies de animais e no homem1,2,3. As alterações oculares nos animais podem fornecer informações importantes ao médico veterinário, já que elas podem ser os primeiros sinais clínicos observados1,2,3. O objectivo desta comunicação foi relatar casos de animais com alterações oftalmológicas, que através do reconhecimento...


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