9 documents found, page 1 of 1
Exploring the possible link between fluoride sensitivity and bacterial defluori...
Maia, Tiago; Carvalho, Maria F.; Alexandrino, Diogo A. M.; Alexandrino, DiogoFluoorganic compounds are ubiquitous environmental pollutants due to their widespread use and high environmental persistence, mostly attributed to the stability of their carbon-fluoride bonds. The biotransformation of these compounds has been observed in some microorganisms, but defluorination (cleavage of carbon-fluorine bonds) remains the limiting step. Intracellular accumulation of fluoride occurs during mic...
Complementary field and laboratory batch studies to quantify generation rates o...
Haluska, Alexander Arthur; Röhler, Klaus; Fabregat-Palau, Joel; Alexandrino, Diogo A. M.; Abramov, Sergey; Thompson, Katharine J.; Straub, DanielSoil microbiome changes and generation rates of per- and polyfluoroalkyl substances (PFAS) precursors were studied in a contaminated agricultural field using a combination of field and laboratory batch microcosm studies. 16S rRNA gene amplicon sequencing was used to track how microbial community composition changed over time, while perfluoroalkyl acids (PFAA) generation rates were quantified using a combination...
Unveiling the culturable and non‐culturable actinobacterial diversity in two ma...
Girão, Mariana; Alexandrino, Diogo A. M.; Cao, Weiwei; Costa, Isabel; Jia, Zhongjun; Carvalho, Maria F.; Alexandrino, DiogoActinomycetota, associated with macroalgae, remains one of the least explored marine niches. The secondary metabolism of Actinomycetota, the primary microbial source of compounds relevant to biotechnology, continues to drive research into the distribution, dynamics, and metabolome of these microorganisms. In this study, we employed a combination of traditional cultivation and metagenomic analysis to investigate...
Actinobacteria from arctic and atlantic deep-sea sediments—biodiversity and bio...
Ribeiro, Inês ; Antunes, Jorge T. ; Alexandrino, Diogo A. M.; Tomasino, Maria Paola ; Almeida, Eduarda ; Hilário, Ana ; Urbatzka, RalphThe deep-sea covers over 70% of the Earth’s surface and harbors predominantly uncharacterized bacterial communities. Actinobacteria are the major prokaryotic source of bioactive natural products that find their way into drug discovery programs, and the deep-sea is a promising source of biotechnologically relevant actinobacteria. Previous studies on actinobacteria in deep-sea sediments were either regionally res...
Combined effects of temperature and dietary lipid level on body composition, gr...
Cardoso, Patrícia G.; Gonçalves, Odete; Cavalheri, Thais; Amorim, Vânia E.; Cao, Weiwei; Alexandrino, Diogo A. M.; Jia, Zhongjun; Carvalho, Maria F.The effects of increasing temperature and dietary lipid level on the body composition, growth performance, and freshness profile of the European seabass (Dicentrarchus labrax) were evaluated through a fish trial lasting 56 days. Findings demonstrated that fish reared at 24 °C presented a lower lipid level and a higher daily growth index than those reared at 20 °C. On the other hand, the sea bass condition index...
Development of a bioremediation system for the removal of PFAS from aquatic env...
Pinto, Ana Sofia; Neves, David M. B.; Maia, Tiago; Mucha, Ana Paula; Almeida, C. Marisa R.; Martins, Pedro; Lanceros-Mendez, SenetxuAmong the many pollutants that afflict aquatic ecosystems, PFAS (per- and polyfluoroalkyl substances) stand out due to their distribution, environmental persistence and ecotoxicity. Currently, there are no suitable remediation technologies capable of mitigating PFAS-related pollution in these ecosystems. Yet, the combination of nanophotocatalysis (NPC) and bioremediation (BRMD) may prove useful in combating PFA...
Assembly of bacterial consortium for the biodegradation of PFAS and related sub...
Neves, David M. B.; Pinto, Ana Sofia; Mucha, Ana Paula; Almeida, C. Marisa R.; Alexandrino, Diogo A. M.; Carvalho, Maria F.; Alexandrino, DiogoPer- and polyfluoroalkyl substances (PFAS) are man-made chemicals with wide application in consumer products since the 1950s. A recent revision of the PFAS definition has also introduced several polyfluorinated pharmaceuticals and agrochemicals into this class, further exacerbating the urgency of any PFAS-related pollution scenario. Their many favourable properties, including improved persistence and lipophilic...
Isolation of Actinomycetes from marine sediments with potential to produce bioa...
Ribeiro, Inês; Alexandrino, Diogo A. M.; Oliveira, Rui S.; Santos, Chiara; Pereira, Filipe; Mucha, Ana P.; Carvalho, Maria F.The various health problems experienced by the humanity, together with an increasing number of antibiotic-resistant microorganisms have been driven scientists to look for additional reserves of new bioactive substances. Actinomycetes are an important source of bioactive compounds with industrial and pharmaceutical interest. The distribution of this vast microbial group in the oceans is largely unexplored, makin...
Microbial degradation of Sodium Trifluoroacetate under aerobic and anaerobic co...
Alexandrino, Diogo A. M.; Oliveira, Rui S.; Carvalho, M. FátimaThe extensive use of hydrofluorocarbons (HFCs) and hydrochlorofluorocarbons (HCFCs) as environmental acceptable alternatives to chlorofluorocarbons (CFCs) has been responsible for the introduction in the environment of significant amounts of Trifluoroacetate (TFA). Specifically, TFA is produced by the atmospheric breakdown of HCFC-123, HCFC-124, HFC-134a and HFO-1234yf, which undergo oxidative, photolytic and h...