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Predictors for incomplete response to ursodeoxycholic acid in primary biliary c...

Cortez-Pinto, Helena; Liberal, Rodrigo; Lopes, Susana; Machado, Mariana; Carvalho, Joana; Dias, Teresa; Santos, Arsénio; Agostinho, Cláudia

Background: The current standard of treatment in primary biliary cholangitis (PBC) is ursodeoxycholic acid (UDCA), although a considerable proportion of patients show incomplete response resulting in disease progression. Objective: This study aimed to assess the prevalence of incomplete response to UDCA and determine associated patients' characteristics. Methods: Patients with PBC as main diagnosis were include...


Outcomes of single-operator cholangioscopy-guided lithotripsy in patients with ...

Canena, Jorge; Lopes, Luís; Fernandes, João; Alexandrino, Gonçalo; Lourenço, Luís; Libânio, Diogo; Horta, David; Giestas, Sílvia; Reis, Jorge

Background and Aims: Endoscopic retrograde cholangiopancreatography is the preferred strategy for the management of biliary and pancreatic duct stones. However, difficult stones occur, and electrohydraulic (EHL) and laser lithotripsy (LL) have emerged as treatment modalities for ductal clearance. Recently, single-operator cholangioscopy was introduced, permitting the routine use of these techniques. We aimed to...


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