Background: Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection, hospitalisation and death in adults. Methods: Based on evidence regarding the impact of RSV on adult populations at risk for severe infection and the efficacy and safety of RSV vaccines, the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society ...
Background: Respiratory syncytial virus (RSV) is an important cause of lower respiratory tract infection, hospitalisation and death in adults. Methods: Based on evidence regarding the impact of RSV on adult populations at risk for severe infection and the efficacy and safety of RSV vaccines, the Portuguese Society of Pulmonology, the Portuguese Association of General and Family Medicine, the Portuguese Society ...
Background: Clinical studies are coordinated by multidisciplinary teams, which often lack adequate training and competencies. In this study, ROCHE and AICIB (Agency for Clinical Research and Biomedical Innovation) conducted a self-assessment survey aiming to evaluate the competency of clinical research professionals to conduct clinical research in Portugal and promote the identification of key actions to addres...
Introduction and objectives: People with interstitial lung diseases (ILD) present a decline in functional status and health-related quality of life (HRQoL). There are several instruments to assess these patient-centered outcomes, however, their measurement properties for specific populations are often unknown. The aim of this study was to assess the reliability and validity of the King’s Brief Interstitial Lung...
Introduction and objectives: There are several instruments to assess functional status, however, their measurement properties for specific populations are often unknown. The aim of this study was to assess the reliability and validity of the Pulmonary Functional Status and Dyspnea Questionnaire - modified version (PFSDQ-M) and the Canadian Occupational Performance Measure (COPM) for Portuguese adults with inter...
The burden of Chronic Obstructive Pulmonary Disease (COPD) is recognised worldwide, constituting a major public health problem due to significant morbidity and mortality. Portugal is not an exception to the impact of the COPD burden. The most recent data for the Portuguese population indicates that COPD is the fifth cause of death, with an estimated prevalence of 14.2% for individuals > 40 years old, as shown i...
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A molecular classifier using a machine-learning algorithm based on genomic data could provide an objective method to aid clinicians and multidisciplinary teams to establish the diagnosis of IPF in less-invasive transbronchial lung biopsy samples https://bit.ly/2QLdWim.
Many publications show an incidence increase of Clostridium difficile (CD) associated disease (CDAD), affecting both in- and outpatients being these recent infections more severe and difficult to treat. The aim of this retrospective study is to evaluate the incidence and clinical impact of CDAD in patients hospitalized from the 1st January 2004 to the 31st December 2009. Suggestive clinical manifestations and a...