12 documents found, page 1 of 2
Biochemical changes in cancer cells induced by photoactive nanosystem based on ...
Nesic, Maja D.; Ducic, Tanja; Gonçalves, Mara; Stepić, Milutin; Algarra, Manuel; Soto, Juan; Gemović, Branislava; Bandosz, Teresa J.; Petkovic, MarijanaCarbon dots (CDs) and N-carbon dots (N-CDs) loaded with Ru-complex (CDs@RuCN, N-CDs@RuCN, respec tively) were investigated as media imposing biochemical changes induced by UV illumination of ovarian cancer, A2780, and osteosarcoma, CAL72, cells. Synchrotron radiation-based Fourier Transform Infrared Spectroscopy was performed, and the spectra were subjected to a Principal Component Analysis. The CDs@RuCN and N ...
Lipid Status of A2780 Ovarian Cancer Cells after Treatment with Ruthenium Compl...
Nesic, Maja D.; Ducic, Tanja; Algarra, Manuel; Popović, Iva; Stepić, Milutin; Gonçalves, Mara; Petkovic, MarijanaIn the last decade, targeting membrane lipids in cancer cells has been a promising approach that deserves attention in the field of anticancer drug development. To get a comprehensive un derstanding of the effect of the drug [Ru(η 5 -Cp)(PPh3 )2CN] (RuCN) on cell lipidic components, we combine complementary analytical approaches, matrix-assisted laser desorption and ionization time of-flight mass spectrometry (...
A coleção científica do Museu do ISEP: as Pilhas de Grenet e Leclanché
Cadeco, Guilhermina; Costa, Patrícia; Campos, Bruno B.; Algarra, Manuel; Martínez de Yuso, Maria Valle; Moreira, Patrícia R.; Silva, PauloO Museu do Instituto Superior de Engenharia do Porto (ISEP), criado em 1999, guarda a memória do ensino industrial da segunda metade do século XIX. Um ensino muito direcionado para a prática do conhecimento que recorria a modelos e instrumentos como metodologia. O acervo museológico é constituído por três grandes coleções: objetos, estampas/desenhos e fotografias, num total de 10000 peças, aproximadamente. A co...
Green chitosan: thiourea dioxide cleaning gel for manganese stains on granite a...
Campos, Bruno; Marco, Alexandra; Cadeco, Guilhermina; Freire-Lista, David M.; Silvestre-Albero, Joaquin; Algarra, Manuel; Vieira, EduardaThe cleaning or removal of manganese stains on Cultural Heritage has not been much tested or successful so far. The aim of this article was to assess a new green cleaning gel for Mn-rich black-blue stains on different substrates. The black-blue stains were characterized at optical and chemical level through colour-related data, optical microscope, FTIR, XRF and XPS. Mn-stained granite found on historical church...
Detection of Ru potential metallodrug in human urine by MALDI-TOF mass spectrom...
Nunes, Nádia; Popović, Iva; Abreu, Elder; Maciel, Dina; Rodrigues, João; Soto, Juan; Algarra, Manuel; Petkovic, MarijanaWe studied the possibility of detection of [Ru(η5 -C5H5)(PPh3)2Cl] (abbreviated by RuCp) complex as a model system for Ru-based metallodrugs in human urine by using matrix-assisted laser desorption/ionization time-of flight mass spectrometry (MALDI-TOF MS) without previous purification or removal of inorganic salts. Inorganic salts might prevent the detection of RuCp by MALDI-TOF MS, most likely through the inc...
Evaluation of the occurrence of phthalates in plastic materials used in food pa...
Perestrelo, Rosa; Silva, Catarina L.; Algarra, Manuel; Câmara, José S.Phthalates are multifunctional synthetic chemicals found in a wide array of consumer and industrial products, mainly used to improve the mechanical properties of plastics, giving them flexibility and softness. In the European Union, phthalates are prohibited at levels greater than 0.1% by weight in most food packaging. In the current study, headspace solid-phase microextraction (HS SPME) combined with gas chrom...
Comprehensive insight from phthalates occurrence: from health outcomes to emerg...
Luís, Catarina; Algarra, Manuel; Câmara, José S.; Perestrelo, RosaPhthalates are a group of chemicals used in a multitude of important industrial products (e.g., medical devices, children’s toys, and food packages), mainly as plasticizers to improve me chanical properties such as flexibility, transparency, durability, and longevity of polyvinyl chloride (PVC). The wide occurrence of phthalates in many consumer products, including foods (e.g., bottled water, soft drinks, wine,...
Chemically heterogeneous carbon dots enhanced cholesterol detection by MALDI TO...
Houdová, Dominika; Soto, Juan; Castro, Rita; Rodrigues, João; Soledad Pino-González, Mª; Petković, Marijana; Bandosz, Teresa J; Algarra, ManuelA binary system composed of carbon dots (CDs) and N-doped CDs (N-CDs) embedded in an organic matrix was used for the analysis of cholesterol by MALDI (matrix-assisted laser desorption and ionization time of-flight) mass spectrometry, as a model for detection of small, biologically relevant molecules. The results showed that both CDs are sensitive to the cholesterol and can be used either alone or in a binary sy...
Green chitosan: thiourea dioxide cleaning gel for manganese stains on granite a...
Campos, Bruno; Marco, Alexandra; Cadeco, Guilhermina; Freire-Lista, David M.; Silvestre-Albero, Joaquin; Algarra, Manuel; Vieira, EduardaThe cleaning or removal of manganese stains on Cultural Heritage has not been much tested or successful so far. The aim of this article was to assess a new green cleaning gel for Mn-rich black-blue stains on different substrates. The black-blue stains were characterized at optical and chemical level through colour-related data, optical microscope, FTIR, XRF and XPS. Mn-stained granite found on historical church...
A coleção científica do Museu do ISEP: as pilhas de Grenet e Leclanché
Cadeco, Guilhermina; Costa, Patrícia; Campos, Bruno B.; Algarra, Manuel; Yuso, M.ª Valle Martínez de; Moreira, Patrícia R.; Silva, PauloO Museu do Instituto Superior de Engenharia do Porto (ISEP), criado em 1999, guarda a memória do ensino industrial da segunda metade do século XIX. Um ensino muito direcionado para a prática do conhecimento que recorria a modelos e instrumentos como metodologia. O acervo museológico é constituído por três grandes coleções: objetos, estampas/desenhos e fotografias, num total de 10 mil peças, aproximadamente. A c...