7 documents found, page 1 of 1
Spiro-ß-lactam BSS-730A Displays Potent Activity against HIV and Plasmodium
Bártolo, Inês; Santos, Bruna S.; Fontinha, Diana; Machado, Marta; Francisco, Denise; Sepodes, Bruno; Rocha, Joao; Mota-Filipe, Hélder; Pinto, RuiThe high burden of malaria and HIV/AIDS prevents economic and social progress in developing countries. A continuing need exists for development of novel drugs and treatment regimens for both diseases in order to address the tolerability and long-term safety concerns associated with current treatment options and the emergence of drug resistance. We describe new spiro-β-lactam derivatives with potent (nM) activit...
Supplements in the EU: an updated analysis of health claims related to articula...
Bettencourt-Câmara, Madalena; Sepodes, Bruno; Bronze, Rosário; Figueira, Maria-Eduardo
Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in ...
Rocha, João; Direito, Rosa; Lima, Ana; Mota, Joana; Gonçalves, Margarida; Duarte, Maria Paula; Solas, João; Peniche, Bruno Felício; Fernandes, AdelaidePurpose - Little is known about the pharmacological effects of the phenolic compounds of Pennyroyal (Mentha pulegium). This Mediterranean aromatic plant, used as a gastronomic spice and as food preservative by the food industry has been studied mainly due to its essential oil antibacterial properties, composed primarily by monoterpenes. With this work, we aimed to evaluate the effects of a phenolic extract of p...
Reduction of inflammation and colon injury by a Pennyroyal phenolic extract in ...
Rocha, João; Direito, Rosa; Lima, Ana; Mota, Joana; Gonçalves, Margarida; Duarte, Maria Paula; Solas, João; Peniche, Bruno Felício; Fernandes, AdelaidePurpose: Little is known about the pharmacological effects of the phenolic compounds of Pennyroyal (Mentha pulegium). This Mediterranean aromatic plant, used as a gastronomic spice and as food preservative by the food industry has been studied mainly due to its essential oil antibacterial properties, composed primarily by monoterpenes. With this work, we aimed to evaluate the effects of a phenolic extract of pe...
Supplements in the European Union: an analysis of health claims related to arti...
Bettencourt-Câmara, Madalena; Sepodes, Bruno; Bronze, Rosário; Figueira, Maria-Eduardo
Hypocholesterolemic effect of green tea and antioxidant effect ofepigallocatech...
Reto, Marcia; Almeida, Cristina M.M.; Barroso, Isabel; Sepodes, Bruno; Pinto, Rui; Mota-Filipe, Helder; Figueira, Maria-Eduardo
Glycogen synthase kinase-3b inhibitor, TDZD-8, attenuates the liver injury caus...
Sepodes, Bruno; Abdelrahman, Maha; Pinto, Rui; Figueira, Maria-Eduardo; Mota-Filipe, Helder; Thiemermann, Christoph