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Vitamin A affects flatfish development in a thyroid hormone signaling and metam...

Fernandez, Ignacio; Ortiz-Delgado, Juan B.; Darias, Maria J.; Hontoria, Francisco; Andree, Karl B.; Manchado, Manuel; Sarasquete, Carmen; Gisbert, Enric

Vitamin A (VA) and retinoid derivatives are known morphogens controlling vertebrate development. Despite the research effort conducted during the last decade, the precise mechanism of how VA induces post-natal bone changes, and particularly those operating through crosstalk with the thyroid hormones (THs) remain to be fully understood. Since effects and mechanisms seem to be dose and time-dependent, flatfish ar...

Date: 2017   |   Origin: Sapientia - Universidade do Algarve
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