34 documents found, page 1 of 4
Polymorphisms and haplotypes of TOLLIP and MUC5B are associated with susceptibi...
Mota, P.C.; Soares, M.L.; Ferreira, A.C.; F. Santos, Rita; Cavaleiro Rufo, J; Vasconcelos, D.; Carvalho, A.; Guimarães, S.; Vasques-Novo, F.Hypersensitivity pneumonitis (HP) is an interstitial lung disease with diverse clinical features that can present a fibrotic phenotype similar to idiopathic pulmonary fibrosis (IPF) in genetically predisposed individuals. While several single nucleotide polymorphisms (SNPs) have been associated with IPF, the genetic factors contributing to fibrotic HP (fHP) remain poorly understood. This study investigated the ...
Can Protective Factors Prevent Antisocial Behaviour? Insights from the PROTECT-...
Santos, M.A.; Fonseca, I.; Guedes, I.; Moreira, S.; Cardoso, C.; Castro, J.; Santos, G.; Gomes, H.
Evaluation of the systemic oxidative stress status upon in vivo exposure to tra...
Cardoso, C.; Dinis-Oliveira, R. J.; Leal, S.; Barbosa, J.; Faria, J.Background: Tramadol and tapentadol are synthetic centrally acting analgesic opioids, used in the treatment of moderate to severe pain [1]. Despite their optimized therapeutic and safety profiles, these compounds are associated with adverse effects, namely CNS and respiratory depression, abuse and dependence [2, 3]. Oxidative stress is one of the main toxicity mechanisms triggered by opioids [1, 4, 5]. Objectiv...
Farming a wild seaweed and changes to its composition, bioactivity, and bioacce...
Cardoso, C.; Almeida, J.; Coelho, I.; Delgado, I.; Gomes, R.; Quintã, R.; Bandarra, N.M.; Afonso, C.The nutritional value, elemental and fatty acid composition as well as key biological activities were determined in a large brown seaweed species (Saccorhiza polyschides, abundant in European shores), taking into account the effects of wild vs farmed and land-based vs open sea Integrated Multi-Trophic Aquaculture (IMTA) system dichotomies. The results showed that S. polyschides has significant amounts of releva...
Elemental composition and in vitro bioaccessibility assessment of holothuroids
Sales, S.S.; Lourenço, H.M.; Bandarra, N.M.; Cardoso, C.; Brito, P.; Botelho, M.J.; Gonçalves, S.; Coelho, I.; Delgado, I.; Pessoa, M.F.; Félix, P.M.The elemental composition and bioaccessibility of the wild holothuroids Holothuria arguinensis, Holothuria forskali, and Holothuria mammata was studied. Nutritional and toxicological aspects were evaluated. H. mammata was the richest in Mn, Ni, As, Cd, Pb, and Hg; H. forskali had the highest Cu and I contents, 4.12–4.93 mg/kg dw and 28.02–28.26 mg/kg dw, respectively; and Summer H. arguinensis had high Se conte...
Seasonal variation of chub mackerel (Scomber colias) selenium and vitamin B12 c...
Rego, A.; Coelho, I.; Motta, C.; Cardoso, C.; Gomes-Bispo, A.; Afonso, C.; Prates, J.A.M.; Bandarra, N.M.; Silva, J.A.L.; Castanheira, I.Chub mackerel (Scomber colias), an underutilised fish species, has been identified as an excellent source of selenium and vitamin B12, which may prevent and delay cognitive decline and dementia. Given these nutrients’ contents seasonal variability, a complete monthly sampling, involving a specifically adjusted methodology for the determination of vitamin B12 (LC-MS/MS) and its main vitamers and a sensitive anal...
The Evaluation of Different Treatments of Incipient Caries Lesions: An in Situ ...
Diniz, M.; Campos, P.; Souza, M. [UNESP]; Guare, R.; Cardoso, C.; Lussi, A.; Bresciani, E. [UNESP]Made available in DSpace on 2021-06-25T15:02:55Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; This study aimed to evaluate in situ the inhibition of incipient caries lesion progression using different treatment protocols and to evaluate the effectiveness of fluorescence-based methods (DIAGNOdent, DIAGNOdent pen, and VistaProof fluorescence camera [FC]) in monitoring this process. The research wa...
Seasonality as experienced in the market and the resulting variation in the ami...
Motta, C.; Rego, A.; Cardoso, C.; Coelho, I.; Gomes-Bispo, A.; Afonso, C.; Prates, J.A.M.; Castanheira, I.; Bandarra, N.Chub mackerel (Scomber colias) is an underutilised fish species, abundant in the Atlantic Ocean. Its amino acid profile and elemental composition are still insufficiently studied. Accordingly, these aspects were studied on a monthly basis. The most abundant essential amino acids, lysine and leucine, had contents ranging from 1270 ± 40 mg/100 g in August to 1820 ± 96 mg/100 g in November and from 1210 ± 36 mg/10...
Human health risk–benefit assessment of fish and other seafood: a scoping review
Thomsen, S.T.; Assunção, Ricardo; Afonso, C.; Boué, G.; Cardoso, C.; Cubadda, F.; Garre, A.; Kruisselbrink, J.; Mantovani, A.; Pitter, J.; Poulsen, M.Fish and other seafood are important sources of nutrients, but they are also sources of chemical contaminants that may cause adverse health effects. This article aimed to identify existing risk–benefit assessments (RBA) of fish, shellfish, and other seafood, compare methodologies, discuss differences and commonalities in findings, and identify limitations and ways forward for future studies. We conducted a scop...
Beverages consumption among students of the University of Porto
Cardoso, C.; Garcia, I.; Martins, J.; Morais, Cecília; Pereira, Bárbara; Almeida, Maria Daniel Vaz de; Poínhos, Rui; Oliveira, B.M.P.M.