With governance increasingly regarded as co-governance, states’ capacity to steer, correct, and discipline a wide range of self-governing actors becomes crucial for states’ effectiveness, efficiency, and democracy. This article investigates that capacity and the relationship between formal institutions and customary self-governance in areas of limited statehood. In South Sudan, the field of land governance can ...
Uma dieta pouco saudável e a falta de exercício produzem mudanças físicas e fisiológicas como a acumulação anormal de gordura corporal, modificações na secreção de hormonas e a perda de equilíbrio da microbiota intestinal, também conhecida por disbiose. A obesidade é uma condição médica cuja prevalência aumenta significativamente todos os anos. Além dos efeitos físicos, potencia o aparecimento de outras condiçõ...
N,N-dimethyl-4-nitroaniline is a piezoelectric organic superplastic and superelastic charge transfer molecular crystal that crystallizes in an acentric structure. Organic mechanical flexible crystals are of great importance as they stand between soft matter and inorganic crystals. Highly aligned poly-l-lactic acid polymer microfibers with embedded N,N-dimethyl-4-nitroaniline nanocrystals are fabricated using th...
PIK3CA mutations are the most common in breast cancer, particularly in the estrogen receptor-positive cohort, but the benefit of PI3K inhibitors has had limited success compared with approaches targeting other less common mutations. We found a frequent allelic expression imbalance between the missense mutant and wild-type PIK3CA alleles in breast tumors from the METABRIC (70.2%) and the TCGA (60.1%) projects. W...
Multiferroic materials demonstrating coexistence of magnetic and ferroelectric orders are promising candidates for magnetoelectric devices. While understanding the underlying mechanism of interplaying of ferroic properties is important, tailoring their properties to make them potential candidates for magnetoelectric devices is challenging. Here, the antiferromagnetic Neel ordering temperature above 200 K is rea...
This study aims to explore the experience of the process of transition to a leadership position, focusing on the strategies that leaders adopt to keep their exploratory behavior active during the transitioning process. The research adopts a qualitative methodology, with life history interviews, in two separate moments. The data reveal the following strategies to keep exploratory behavior active: developing skil...
The multifunctionality of Energy Storage Systems (ESS) has being viewed as a powerful resource for a stable and reliable grid operation in an environment of high DER penetration at all voltage levels. The Portuguese DSO, EDP Distribuição, established a multi-sourced partnership with Siemens and the University of Évora, to implement, test and execute a pioneer Energy Storage project. A medium-voltage (15kV) stor...
This work reports the deposition of single phase Bi2ZnTiO6 thin films onto Pt/Si-based substrates using the RF-sputtering method and the respective structural, morphological, optical and local ferroelectric characterization. The thin film grows in the polycrystalline form with tetragonal P4mm symmetry identified by X-ray diffraction. The lack of a spatial inversion centre was confirmed by the second harmonic ge...
Background Breast cancer is a highly heterogeneous disease resulting in diverse clinical behaviours and therapeutic responses. DNA methylation is a major epigenetic alteration that is commonly perturbed in cancers. The aim of this study is to characterize the relationship between DNA methylation and aberrant gene expression in breast cancer. Methods We analysed DNA methylation and gene expression profiles from ...