51 documents found, page 1 of 6
De estação em estação, transforma-se a educação: o uso da metodologia de rotaçã...
Almeida, Catarina; Vieira, Natacha; Dias Graça, Vânia GabrielaA metodologia ativa de Rotação por Estações promove a construção ativa do conhecimento, estimulando a autonomia e a participação dos alunos. Esta comunicação insere-se no projeto “Aprender com Respeito”, desenvolvido no âmbito da Prática Educativa Supervisionada numa turma do 2.º ano do 1.º Ciclo do Ensino Básico. A unidade de aprendizagem “Porque devemos respeitar os animais?” teve como objetivo sensibilizar o...
Impact of Concordance Between Antinuclear Antibody Indirect Immunofluorescence ...
Pinto Oliveira, Cláudia; Pereira Silva, Mariana; Vilafanha, Carolina; Costa, Graça; Santos, Mariana Emília; Gonçalves, Maria João; Silva, PriscilaIdiopathic inflammatory myopathies (IIM) are a heterogeneous group of systemic autoimmune rheumatic disorders in which chronic inflammation of skeletal muscle leads to muscle weakness. Many other organs, including the skin, heart, lungs, and joints, may be affected. Patients with IIM may be positive for myositis antibodies (MAs), including myositis-specific and/or associated antibodies. Although helpful for est...
Innovation in local Public Administrations at the European Level
Barbedo, Inês; Costa, Cláudia S.; Martins, Márcio Ribeiro; Silva, Catarina; Barroso, Bárbara; Gomes, Carina; Ribeiro, Catarina; Mota, LuísThe Bragança Polytechnic University in Portugal (IPB), in collaboration with the Foundation for Studies and Training in Local Administration (FEFAL), the National Institute of Administration (INA, I. P.), the City University of Applied Sciences Bremen in Germany (HSB), and the Silesian University in Opava in the Czech Republic (SUO), are spearheading a project to thoroughly analyze the culture of innovation in ...
O posicionamento predominante das termas do Luso nos serviços de bem-estar
Moura, Filipa; Almeida, Catarina; Viegas, Andreia; Antunes, Joaquim; Costa, JoãoEste estudo tem como objetivo estudar as motivações dos frequentadores das termas em Portugal, com destaque para os frequentadores da estância do Luso, procurando analisar as suas diferenças. Pretende-se ainda analisar a imagem das termas, de modo a que as organizações consigam responder às novas exigências da procura.
Motivações e desafios no voluntariado em contexto hospitalar: um estudo qualita...
Almeida, Patrícia; Martins, Andreia; Chaves, Carolina; Almeida, Catarina; Silva, Isabel S.; Bártolo, AnaA investigação tem sugerido que o voluntariado emerge como uma forma de envolvimento na comunidade estando associado a bem-estar físico e emocional. No entanto, as exigências subjacentes a um contexto de prestação de cuidados de saúde podem constituir-se como um desafio adicional e impactar negativamente as experiências e motivações dos indivíduos. O presente estudo objetivou explorar os fatores motivadores e d...
Voluntary exercise attenuates inflammaging in mice
Melo-Miranda, Rita; Silva, Catarina; Almeida, Catarina; Sousa, AnaAging, one of the biggest health challenges of our time, is accompanied by numerous events, including an increase in inflammation levels (a process known as “inflammaging”), intestinal permeability, and dysbiotic alterations in the intestinal microbiota. Gut bacterial dysbiosis contributes to aging by increasing gut permeability and giving rise to systemic inflammation, thus feeding this positive feedback loop....
Ionic-liquid-based approaches to improve biopharmaceuticals downstream processi...
Almeida, Catarina; Pedro, Augusto Q.; Tavares, Ana P. M.; Neves, Márcia C.; Freire, Mara G.The emergence of biopharmaceuticals, including proteins, nucleic acids, peptides, and vaccines, revolutionized the medical field, contributing to significant advances in the prophylaxis and treatment of chronic and life-threatening diseases. However, biopharmaceuticals manufacturing involves a set of complex upstream and downstream processes, which considerably impact their cost. In particular, despite the effo...
Microbial evolutionary signatures of longevity in very old mice
Melo-Miranda, Rita; Sousa, Ana; Almeida, Catarina; Martinho, RuiAging, one of the biggest health challenges of our time, is associated with several occurrences, including an increase in inflammation and gut microbial dysbiosis. These events contribute to aging by rising intestinal permeability and inflammation, but it remains undisclosed how they influence microbiota evolution and pathobiont selection. Here we approach this question by comparing microbial evolution in the g...
Microbiota evolution in the inflamed gut
Silva, Catarina Almeida; Almeida, Catarina; Sousa, Ana MargaridaLow grade inflammation (LGI) is associated with ageing and several pathologic conditions such as inflammatory bowel disease, cardiovascular disease, cancer, diabetes, obesity, autoimmune and neurodegenerative disorders. It is known that inflammation can affect and be affected by microbiota dysbiosis. However, this raises several questions: What are the effects of prolonged inflammation in microbial evolution? A...
High performance of ionic-liquid-based materials to remove insecticides
Francisco, Rafael; Almeida, Catarina; Sousa, Ana C. A.; Neves, Márcia C.; Freire, Mara G.Neonicotinoids are systemic insecticides commonly used for pest control in agriculture and veterinary applications. Due to their widespread use, neonicotinoid insecticides (neonics) are found in different environmental compartments, including water, soils, and biota, in which their high toxicity towards non-target organisms is a matter of great concern. Given their widespread use and high toxicity, the developm...