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An Exemestane Derivative, Oxymestane-D1, as a New Multi-Target Steroidal Aromat...
Amaral, Cristina; Correia-da-Silva, Georgina; Almeida, Cristina Ferreira; Valente, Maria João; Varela, Carla; Tavares-da-Silva, ElisiarioAround 70-85% of all breast cancer (BC) cases are estrogen receptor-positive (ER+). The third generation of aromatase inhibitors (AIs) is the first-line treatment option for these tumors. Despite their therapeutic success, they induce several side effects and resistance, which limits their efficacy. Thus, it is crucial to search for novel, safe and more effective anti-cancer molecules. Currently, multi-target d...
Data: 2023
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Origem: Estudo Geral - Universidade de Coimbra