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Gla-rich protein (GRP) as an early and novel marker of vascular calcification a...

Silva, Ana P.; Viegas, Carla; Mendes, Filipa; Macedo, Ana; Guilherme, Patrícia; Tavares, Nelson; Dias, Carolina; Rato, Fátima; Santos, Nélio

Vascular calcification (VC) is one of the strongest predictors of cardiovascular risk in chronic kidney disease (CKD) patients. New diagnostic/prognostic tools are required for early detection of VC allowing interventional strategies. Gla-rich protein (GRP) is a cardiovascular calcification inhibitor, whose clinical utility is here highlighted. The present study explores, for the first time, correlations betwee...


Homozygous C677T mutation of the 5,10-methylenetetrahydrofolate reductase gene ...

Guimaraes, Nuno; Silva, Sónia; Branco, Patrícia; Almeida, Edgar de; Canhão, Patrícia; Barbas, José; Gomes da Costa, A.; Prata, M. Martins

We report a case of a cerebral venous thrombosis (CVT) in a chronic kidney disease patient with three CVT predisposing conditions. A 53 year-old woman on chronic peritoneal dialysis presented to the emergency department with acute headache and vertigo. The neurological examination and head CT scan performed at the emergency department were normal but, three days later, a lateral gait deviation and a horizontal ...


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