5 documents found, page 1 of 1
Acyl homoserine lactone-based quorum sensing stimulates biofilm formation by Sa...
Almeida, Felipe Alves de; Pimentel-Filho, Natan de Jesus; Pinto, Uelinton Manoel; Mantovani, Hilário Cuquetto; Oliveira, Leandro Licursi deQuorum sensing regulates a variety of phenotypes in bacteria including the production of virulence factors. Salmonella spp. have quorum sensing systems mediated by three autoinducers (AI-1, AI-2, and AI-3). The AI-1-mediated system is incomplete in that the bacterium relies on the synthesis of signaling molecules by other microorganisms. This study aimed to evaluate the influence of the AI-1 N-dodecanoyl-DL-hom...
N-dodecanoyl-homoserine lactone influences the levels of thiol and proteins rel...
Almeida, Felipe Alves de; Carneiro, Deisy Guimarães; Barros, Edvaldo; Pinto, Uelinton Manoel; Oliveira, Leandro Licursi deQuorum sensing is a cell-cell communication mechanism mediated by chemical signals that leads to differential gene expression in response to high population density. Salmonella is unable to synthesize the autoinducer-1 (AI-1), N-acyl homoserine lactone (AHL), but is able to recognize AHLs produced by other microorganisms through SdiA protein. This study aimed to evaluate the fatty acid and protein profiles of S...
Virtual screening of plant compounds and nonsteroidal anti-inflammatory drugs f...
Almeida, Felipe Alves de; Vargas, Erika Lorena Giraldo; Carneiro, Deisy Guimarães; Pinto, Uelinton Manoel; Vanetti, Maria Cristina DantasSalmonella belongs to the Enterobacteriaceae family which is widely distributed in the environment due to its adaptive capacity to stress conditions. In addition, Salmonella is able to perform a type of cell-to-cell communication called quorum sensing, which leads to differential gene expression. The quorum sensing system mediated by AI-1, acyl homoserine lactones (AHLs), is incomplete in Salmonella because the...
Novel insights from molecular docking of SdiA from Salmonella enteritidis and E...
Almeida, Felipe Alves de; Pinto, Uelinton Manoel; Vanetti, Maria Cristina DantasQuorum sensing is a cell-to-cell communication mechanism leading to differential gene expression in response to high population density. The autoinducer-1 (AI-1) type quorum sensing system is incomplete in Escherichia coli and Salmonella due to the lack of the AI-1 synthase (LuxI homolog) responsible for acyl homoserine lactone (AHL) synthesis. However, these bacteria encode the AHL receptor SdiA (a LuxR homolo...
Influência do quorum sensing na formação de biofilme e no perfil de expressão d...
Almeida, Felipe Alves deConselho Nacional de Desenvolvimento Científico e Tecnológico; Quorum sensing (QS) é um mecanismo de comunicação entre células microbianas mediado por moléculas sinalizadoras, denominadas autoindutores (AIs). Embora não produza o AI-1, que são moléculas de acil homoserina lactonas (AHLs), Salmonella responde às AHLs produzidas por outros micro-organismos por sintetizar a proteína de resposta ao AI-1, denominada...