5 documents found, page 1 of 1
Aspectos farmacológicos das novas norcucurbitacinas glicosídicas de wilbrandia ...
Almeida, Fernanda Regina de CastroThe purified fraction of the rhizome of Wilbrandia (cf) vertiçillata (cabeça de negro) that contained two novel norcucurbitacin glucosides and identified as Wv^ and WV2 was investigated for its possible anti-inflammatory, an tifertility, laxative and cytotoxic cffects. In mice, the LD^g values for the fraction by ip and oral routes wcre 345 1 11 and 975 1 99 mg/kg respecti vely while in KB cell lines, it demons...
Alpha-terpineol: evaluation and pharmacological screening as an antidepressant ...
Assunção , Amanda Fonseca Costa; Rodrigues, Nícolas Davidson Sérvulo; Sampaio, Andreia Viana da Costa; Silva, Karolinny dos SantosObjective: To evaluate the possible antidepressant effects of alpha-terpineol in rodents. Material and Methods: Depression levels were analyzed by comparing the total immobility time presented by the animals of the experimental groups in the test session, using the Forced Swimming Test and the Tail Suspension Test. The parameters of locomotion (central, peripheral and total) and motor coordination were evaluate...
Attenuation of capsaicin-induced acute and visceral nociceptive pain by a - and...
Oliveira, Francisco A.; Costa, Charllynton L.S.; Chaves, Mariana H.0; Almeida, Fernanda Regina de Castro; Cavalcante, Ítalo José MesquitaThe triterpene mixture, a - and h -amyrin, isolated from Protium heptaphyllum resin was evaluated on capsaicin- evoked nociception in mice. Orally administered a - and h -amyrin (3 to 100 mg/kg) significantly suppressed the nociceptive behaviors—evoked by either subplantar (1.6 A g) or intracolonic (149 A g) application of capsaicin. The antinociception produced by a - and h -amyrin against subplantar capsaicin...
Effects of administering testosterone undecanoate in rats subjected to physical...
Silva, Moisés Tolentino Bento da; Martins, Maria do Carmo de Carvalho e; Torres-Leal, Francisco Leonardo; Barros, Talvany LuizThe aim of the work was evaluate the effects of testosterone undecanoate (TU) treatment combined with moderate physical training on: the estrous cycle, body weight (BW), motor behavior (MB), and the morphohistology of the reproductive system, the liver and kidney in rats. Female Wistar rats (180 g - 250 g) were divided as follows: sedentary + TU (S + TU), trained + TU (T + TU), sedentary + vehicle (S + V), trai...
Effects of administering testosterone undecanoate in rats subjected to physical...
Bento-Silva, Moisés Tolentino; Martins, Maria do Carmo de Carvalho e; Torres-Leal, Francisco Leonardo; Barros, Talvany LuizThe aim of the work was evaluate the effects of testosterone undecanoate (TU) treatment combined with moderate physical training on: the estrous cycle, body weight (BW), motor behavior (MB), and the morphohistology of the reproductive system, the liver and kidney in rats. Female Wistar rats (180 g - 250 g) were divided as follows: sedentary + TU (S + TU), trained + TU (T + TU), sedentary + vehicle (S + V), trai...