69 documents found, page 1 of 7

Nursing School of Viseu, 50 years of a benefit

Introduction: In the first half of the 20th century, the portuguese government recognised the shortage of nurses throughout the country and promoted legal changes in the 40s and 50s. In addition to the nursing schools located in the three main portuguese cities, there was a need to spread nursing education throughout the country, with schools springing up in almost every district centre, such as Viseu. Objectiv...

The challenging management of acute mesenteric ischemia - too frail or too late?

INTRODUCTION: acute mesenteric ischemia (AMI) presents a life-threatening emergency, requiring a high degree of suspicion for timely diagnosis. Despite advancements in the management of these patients, in-hospital mortality rates remain high. This study aims to assess the outcomes and prognostic factors in patients with AMI. METHODS: A retrospective single-center analysis of all patients undergoing emergent sur...

Proteomics characterization of human uterine samples during reproductive ageing

Nowadays, postponing motherhood has become more common in modern societies. Such decision rises major social and health concerns, as advanced maternal age associates with low fertility, pregnancy complications and a greater need for assisted reproductive techniques. Female reproductive ageing is associated with alterations that are particularly evident in the ovaries. Yet, given the pivotal contribution of the ...

Addressing the role of maternal age on the metabolic profile of the placenta

After the age of 35, during pregnancy, there is an increased risk of impaired placentation. Changes in uterine redox balance seem to play a role in deficient placentation. We hypothesized that this local redox dysregulation has a negative impact on the placenta metabolic profile. Thus, we aimed to study the placenta metabolic profile during reproductive aging and the effect of antioxidant supplementation. Place...

Unveiling uterine senescence and its potential role in age-related female ferti...

Nowadays, infertility is a major topic present in public health discussions due to its increased prevalence worldwide. With time, female infertility rates have increased, mainly, because women are delaying childbearing to their late 30s/early 40s, leading to fertility decline, complications during gestation, and a higher demand for assisted reproductive techniques. Uterine alterations have been pointed out as a...

Proteomics Characterization of Human Uterine Samples During Reproductive Ageing

Addressing the role of maternal age on the metabolic profile of the placenta

Evaluation of the structural strength of anisotropic PLA components manufacture...

Predicting the mechanical strength of components manufactured by additive processes is a challenging task that is difficulted by the complexity of the geometries fabricated by these processes, along with the anisotropy enhanced by the layer-by-layer manufacturing method and the difficulty in quickly obtaining the elastic and strength properties of the materials, which are strongly influenced by the manufacturin...

Outcomes of kidney autotransplantation technique in the treatment of different ...

INTRODUCTION: Kidney autotransplantation (KAT) is a versatile surgical technique used to treat multiple diseases affecting the kidney. This procedure allows the reconstruction of the renal artery or vein with optimal surgical exposure reducing warm ischemia time compared to open direct repair. Although infrequently reported nowadays and despite the growing use of endovascular treatments, KAT still has a place i...

The Unmet Needs for Studying Chronic Pelvic/Visceral Pain Using Animal Models

<jats:p>The different definitions of chronic pelvic/visceral pain used by international societies have changed over the years. These differences have a great impact on the way researchers study chronic pelvic/visceral pain. Recently, the role of systemic changes, including the role of the central nervous system, in the perpetuation and chronification of pelvic/visceral pain has gained weight. Consequently, rese...