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Acute Coronary Syndrome and Stress: Is There a Relationship?

Santos, H; Santos, M; Paula, S; Figueiredo, M; Almeida, I; Miranda, H; Chin, J; Sá, C; Neto, M; Almeida, S; Sousa, C; Almeida, L

Introduction: Acute coronary syndrome (ACS) is the result of a complex pathophysiological process with various dynamic factors. The 10-item Perceived Stress Scale (PSS-10) is a validated instrument for estimating stress levels in clinical practice and may be useful in the assessment of ACS. Methods: We carried out a single-center prospective study engaging patients hospitalized with ACS between March 20, 2019 a...


A Systemic Review of Endocardial Left Ventricular Pacing

Santos, H; Santos, M; Almeida, I; Paula, S; Figueiredo, M; Portugal, G; Valente, B; Silva Cunha, P; Almeida, L; Oliveira, MM

Background: Endocardial left ventricular pacing is an alternative technique used in cardiac resynchronization therapy (CRT), when placement of a left ventricular lead is not possible via the coronary sinus or in non-responders to conventional CRT. Objectives: To review the evidence regarding the efficacy and safety of endocardial left ventricular pacing. Methods: Systematic research on Medline (PubMed), Clinica...


Long-Term Outcomes of Non-Contact Multi-Electrode Balloon Catheter Mapping-Guid...

Almeida, I; Lousinha, A; Silva Cunha, P; Valente, B; Paulo, M; Delgado, AS; Cruz Ferreira, R; Oliveira, MM

Introduction: The outflow tract (OT) regions of the ventricles are a common location of origin for idiopathic ventricular arrhythmias (VA). Non-contact mapping (NCM) with a multi-electrode balloon catheter Ensite-Array enables three-dimensional reconstruction of the geometry of the cardiac chambers and accurate mapping of the propagation map, based on a single beat analysis, facilitating the ablation and contri...



Spirometry Outside the Hospital

Morais-Almeida, M; Barbosa, MT; Sousa, CS; Almeida, I; Pimenta, L; Aguiar, R

Date: 2021   |   Origin: Saúde - CUF

Tirosinemia Tipo 1: O Passado e o Presente Numa Unidade de Doenças Metabólicas

Oliveira, J; Rodrigues, M; Costa, C; Janeiro, P; Almeida, I; Vilarinho, L; Gaspar, A

Introdução: A ti rosinemia ti po I é uma doença hereditária do metabolismo por défi ce de fumarilacetoacetase, com uma pre- valência ao nascimento de 1:100000 e potencialmente fatal. O plano alimentar individualizado, o transplante hepato-renal e a niti sinona são algumas das estratégias terapêuti cas. Métodos: Estudo retrospeti vo, observacional e descriti vo de oito doentes acompanhados numa unidade de doenças...


Estimating glomerular filtration rate in acute coronary syndromes: Different eq...

Almeida, I; Caetano, F; Barra, S; Madeira, M; Mota, P; Leitão-Marques, A

AIMS: Renal dysfunction is a powerful predictor of adverse outcomes in patients hospitalized for acute coronary syndrome. Three new glomerular filtration rate (GFR) estimating equations recently emerged, based on serum creatinine (CKD-EPIcreat), serum cystatin C (CKD-EPIcyst) or a combination of both (CKD-EPIcreat/cyst), and they are currently recommended to confirm the presence of renal dysfunction. Our aim wa...


Imbalance in habitual versus goal directed neural systems during symptom provoc...

Banca, P; Voon, V; Vestergaard, MD; Philipiak, G; Almeida, I; Pocinho, F; Relvas, J; Castelo-Branco

Intrusive thoughts and compulsive urges to perform stereotyped behaviours are typical symptoms of obsessive-compulsive disorder. Emerging evidence suggests a cognitive bias towards habit formation at the expense of goal-directed performance in obsessive-compulsive disorder. In this study, we test this hypothesis using a novel individualized ecologically valid symptom provocation design: a live provocation funct...


Phenotypic expression in hypertrophic cardiomyopathy and late gadolinium enhanc...

Caetano, F; Botelho, A; Trigo, J; Silva, J; Almeida, I; Venâncio, M; Pais, J; Sanches, C; Leitão-Marques, A

INTRODUCTION AND AIM: The prognostic value of late gadolinium enhancement (LGE) for risk stratification of hypertrophic cardiomyopathy (HCM) patients is the subject of disagreement. We set out to examine the association between clinical and morphological variables, risk factors for sudden cardiac death and LGE in HCM patients. METHODS: From a population of 78 patients with HCM, we studied 53 who underwent cardi...


HIV-2 Integrase Polymorphisms and Longitudinal Genotypic Analysis of HIV-2 Infe...

Cavaco-Silva, J; Abecasis, A; Miranda, AC; Poças, J; Narciso, J; Águas, MJ; Maltez, F; Almeida, I; Germano, I; Diniz, A; Gonçalves, MF; Gomes, P

To characterize the HIV-2 integrase gene polymorphisms and the pathways to resistance of HIV-2 patients failing a raltegravir-containing regimen, we studied 63 integrase strand transfer inhibitors (INSTI)-naïve patients, and 10 heavily pretreated patients exhibiting virological failure while receiving a salvage raltegravir-containing regimen. All patients were infected by HIV-2 group A. 61.4% of the integrase r...


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