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Treatment patterns and preferences of people living with HIV starting or switch...

Pedro, L; Zagalo, A; Tavares, R; Pacheco, P; Oliveira, J; Vaz Pinto, I; Serrão, R; Tavares, S; Brito, P; Maltez, F; Neves, I; Carvalho, A; Teófilo, E

Background: There is a lack of up-to-date real-life evidence on antiretroviral therapy (ART) strategies among people living with HIV (PLWH) in Portugal. This study aimed to describe the treatment strategy used in PLWH either initiating or switching ART. Methods: Non-interventional, cross-sectional, multicenter study carried out between December 2019 and October 2021 in Portugal. Results: A total of 237 PLWH wer...

Date: 2024   |   Origin: Hospital de Cascais

Complete blood count parameters as biomarkers of retinopathy of prematurity: a ...

Fevereiro-Martins, M; Santos, AC; Marques-Neves, C; Guimarães, H; Bicho, M; Afonso, C; Ferreira, J; Espírito Santo, R; Teixeira, F; Rosa, R

Purpose: To evaluate complete blood count (CBC) parameters in the first week of life as predictive biomarkers for the development of retinopathy of prematurity (ROP). Methods: Multicenter, prospective, observational study of a cohort of preterm infants born with gestational age (GA) < 32 weeks or birth weight < 1500 g in eight Portuguese neonatal intensive care units. All demographic, clinical, and laboratory d...

Date: 2023   |   Origin: Saúde - CUF

The red seaweed Grateloupia turuturu prevents epidermal dysplasia in HPV16-tran...

Almeida, J; Ferreira, T; Santos, S; Pires, MJ; Gil da Costa, RM; Medeiros, R; Bastos, MMSM; Neuparth, MJ; Faustino-Rocha, AI; Abreu, A; Pereira, R

Abstract: The role of dietary profiles in promoting or reducing the risk of multiple types of cancer is increasingly clear, driving the search for balanced foods and nutraceuticals. The red seaweed Grateloupia turuturu has been used as human food showing a balanced nutritional profile. This study aims to test in vivo chemopreventive effects of G. turuturu against cutaneous pre-malignant lesions in transgenic mi...


Impact of montelukast as add on treatment to the novel coronavirus pneumonia (C...

Tavares, M; Farraia, M; Silva, S; Ribeiro, AM; Severo, M; Paciência, I; Ribeiro, R; Hespanhol, V; Guimarães, T; Almeida, J; Magro, F; Sarmento, A

Background: Montelukast, a safe drug widely use in asthmatic patients, may be an adjuvant in the treatment of Covid-19, either by improving lung injury and inflammation, or by acting as an anti-viral drug. We aim to assess the efficacy and safety of montelukast as add-on treatment in patients with Covid-19. Methods: We propose a randomized, controlled, parallel, open-label trial involving 160 hospitalized adult...


Recommendations for genetic testing in cardiology: Review of major internationa...

Sousa, A; Moldovan, O; Lebreiro, A; Bourbon, M; António, N; Rato, Q; Rodrigues, P; Toste, A; Gonçalves Rocha, M; Oliveira, R; Granja, S; Cruz, C

In recent years, the importance of genetic causes of cardiovascular diseases has been increasingly recognized, as the result of significant advances in molecular diagnosis techniques. This growing knowledge has enabled the identification of new phenotypes and the subclassification of clinical syndromes, impacting the therapeutic approach and genetic counseling offered to affected families. This paper describes ...



Non-AIDS-Related Comorbidities in People Living with HIV-1 Aged 50 Years and Ol...

Serrão, R; Piñero, C; Velez, J; Coutinho, D; Maltez, F; Lino, S; Sarmento E Castro, R; Tavares, AP; Pacheco, P; Lopes, MJ; Mansinho, K; Miranda, AC

Objective: To characterize the profile of non-AIDS-related comorbidities (NARC) in the older HIV-1-infected population and to explore the factors associated with multiple NARC. Methods: This was a multicentre, cross-sectional study including HIV-1-infected patients aged ≥50 years, who were virologically suppressed and had been on a stable antiretroviral therapy (ART) regimen for at least 6 months. A multiple re...


Internamentos Prolongados numa Enfermaria de Medicina Interna

Pocinho, R; Jardim, S; Antunes, L; Isidoro Duarte, T; Baptista, I; Almeida, J

Introdução: As enfermarias de Medicina Interna acolhem doentes complexos, com múltiplas comorbilidades, idosos, frágeis, dependentes, frequentemente com problemas sociais, podendo condicionar internamentos longos. Pretende-se caracterizar a população com internamentos prolongados (IPs), avaliando se foram adequados à situação clínica ou relacionados com questões socioeconómicas. Métodos: Estudo retrospetivo rea...


Simultaneous removal of trace elements from contaminated waters by living Ulva ...

Henriques, B; Teixeira, A; Figueira, P; Reis, AT; Almeida, J; Vale, C; Pereira, E

This work shows the capabilities of living seaweed, Ulva lactuca, to remove As, Cd, Pb, Cu, Cr, Hg, Mn and Ni from contaminated waters. Experiments were performed with three algal doses (1.5, 3.0 and 6.0 g L−1, FW), two ionic strengths (salinity 15 and 35), and trace element concentrations corresponding to the maximum allowed values in wastewaters. The highest removals were obtained with the algal dose of 6 g L...


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