2 documents found, page 1 of 1
A porcine circovirus-2 mutant isolated in Brazil contains low-frequency substit...
Salgado, Rafael Locatelli; Vidigal, Pedro Marcus Pereira; Gonzaga, Natalia F.; Souza, Luiz F. L. de; Polêto, Marcelo D.; Onofre, Thiago SouzaPorcine circovirus-2 (PCV2) is the etiologic agent of several diseases in pigs, including multi-systemic wasting syndrome (PMWS). In this work, a new mutant PCV2b was isolated from PMWS-affected pigs on a Brazilian farm. Its genome showed high sequence similarity (>99 % identity) to those from a group of emerging mutants isolated from cases of PMWS outbreaks in vaccinated pigs in China, the USA and South Korea....
Identification of an emergent porcine circovirus-2 in vaccinated pigs from a br...
Salgado, Rafael L.; Vidigal, Pedro M. P.; Souza, Luiz F. L. de; Onofre, Thiago S.; Gonzaga, Natália F.; Eller, Monique R.; Bressan, Gustavo C.Three porcine circovirus-2 strains were isolated from pigs on a Brazilian farm during an outbreak, indicating a vaccine failure. They present identical genomic sequences, with high identities to other isolates that were also related to vaccination failures, supporting the recent theory about an antigen drift being associated with vaccine failures throughout the world.