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Rhinitis associated with asthma is distinct from rhinitis alone: TARIA‐MeDALL h...

Bousquet, Jean; Melén, Erik; Haahtela, Tari; Koppelman, Gerard; Togias, Alkis; Valenta, Rudolf; Akdis, Cezmi; Czarlewski, Wienczyslawa; Rothenberg, Marc

Asthma, rhinitis, and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of “one-airway-one-disease,” coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhiniti...

Date: 2023   |   Origin: uBibliorum

Digitally‐enabled, patient‐centred care in rhinitis and asthma multimorbidity: ...

Bousquet, Jean; Anto, Josep M.; Sousa-Pinto, Bernardo; Czarlewski, Wienczyslawa; Bedbrook, Anna; Haahtela, Tari; Klimek, Ludger; Pfaar, Oliver

MASK‐air®, a validated mHealth app (Medical Device regulationClass IIa) has enabled large observational implementation studies in over 58,000 people with allergic rhinitis and/or asthma. It can help to address unmet patient needs in rhinitis and asthma care. MASK‐air® is a Good Practice of DG Santé on digitally‐enabled, patient‐centred care. Itis also a candidate Good Practice ofOECD (Organisation for EconomicC...

Date: 2023   |   Origin: uBibliorum

Patient‐centered digital biomarkers for allergic respiratory diseases and asthm...

Bousquet, Jean; Shamji, Mohamed; Anto, Josep M.; Schünemann, Holger; Canonica, Giorgio Walter; Jutel, Marek; Del Giacco, Stafano; Zuberbier, Torsten

Biomarkers for the diagnosis, treatment and follow-up of patients with rhinitis and/ or asthma are urgently needed. Although some biologic biomarkers exist in specialist care for asthma, they cannot be largely used in primary care. There are no validated biomarkers in rhinitis or allergen immunotherapy (AIT) that can be used in clinical practice. The digital transformation of health and health care (including m...

Date: 2023   |   Origin: uBibliorum

Management of anaphylaxis due to COVID-19 vaccines in the elderly

Bousquet, Jean; Agache, Ioana; Blain, Hubert; Jutel, Marek; Ventura, Maria Teresa; Worm, Margitta; Del Giacco, Stefano; Benetos, Athanasios

Older adults, especially men and/or those with diabetes, hypertension and/or obesity, are prone to severe COVID-19. In some countries, older adults, particularly those residing in nursing homes, have been prioritised to receive COVID-19 vaccines due to high risk of death. In very rare instances,the COVID-19 vaccines can induce anaphylaxis, and the management of anaphylaxis in older people should be considered c...

Date: 2021   |   Origin: uBibliorum

ARIA 2019: Um Percurso Assistencial Integrado para a Rinite Alérgica em Portugal

Fonseca, Joao A; Gomes, Tiago Taveira; Pereira, Ana Margarida; Ferreira, Manuel Branco; Martins, Pedro Carreiro; Correia, Magna Alves

A iniciativa Allergic Rhinitis and Its Impact on Asthma (ARIA) teve início há mais de 20 anos e tem elaborado e disseminado orientações baseadas em evidência, e desenvolvido projetos na área da rinite alérgica. Esta iniciativa está atualmente focada em proporcionar orientações centradas no doente que contribuam para um percurso integrado entre os vários níveis de cuidados e que tirem partido de soluções digitai...

Date: 2021   |   Origin: uBibliorum

ARIA-EAACI care pathways for allergen immunotherapy in respiratory allergy

Bousquet, Jean; Pfaar, Oliver; Agache, Ioana; Bedbrook, Anna; Akdis, Cezmi; Canonica, Giorgio Walter; Chivato, Tomas; Al-Ahmad, Mona; Rasib, A. H. Abdul

Allergen immunotherapy (AIT), the gradually increasing repeated administration of high doses of allergens to allergic patients, offers the potential for immune tolerance against reactions to the natural exposures to specific allergens. AIT may lead to the long‐lasting remission of allergic symptoms and is the only disease‐modifying intervention in IgE‐mediated allergic respiratory diseases. [...]

Date: 2021   |   Origin: uBibliorum

ARIA pharmacy 2018: Allergic rhinitis care pathways for community pharmacy

Bosnic-Anticevich, Sinthia; Costa, Elísio; Menditto, Enrica; Lourenço, Olga; Novellino, Ettore; Bialek, Slawomir; Briedis, Vitalis; Buonaiuto, Roland

Pharmacists are trusted health care professionals. Many patients use over-the-counter (OTC) medications and are seen by pharmacists who are the initial point of contact for allergic rhinitis management in most countries. The role of pharmacists in integrated care pathways (ICPs) for allergic diseases is important. This paper builds on existing studies and provides tools intended to help pharmacists provide opti...

Date: 2019   |   Origin: uBibliorum

Imunizações e Hipersensibilidade a Proteínas de Ovo

Carvalho, Francisca; Agro, João; Almeida, Mário Morais; Rosado Pinto, José Eduardo

A segurança da administração da vacina do sarampo em indivíduos com hipersensibilidade ao ovo tem sido motivo de controvérsia, dado o receio de uma eventual reacção anafiláctica após a vacina, uma vez que o vírus vivo atenuado utilizado em algumas preparações é cultivado em fibroblastos de embrião de frango. É apresentada uma revisão da literatura sobre resultados de estudos destinados a avaliar a ocorrência de...


Validation of control of allergic rhinitis and asthma test for children (CARATK...

Linhares, Daniela V. B. R.; Fonseca, João Almeida L. da; Borrego, Luís Miguel; Matos, Águeda; Pereira, Ana Margarida; Sousa, Ana Sá; Gaspar, Ângela

BACKGROUND: Control of Allergic Rhinitis and Asthma Test for Children (CARATKids) is the first questionnaire that assesses simultaneously allergic rhinitis and asthma control in children. It was recently developed, but redundancy of questions and its psychometric properties were not assessed. This study aimed to (i) establish the final version of the CARATKids questionnaire and (ii) evaluate its reliability, re...


Control of Allergic Rhinitis and Asthma Test (CARAT) : dissemination and applic...

Azevedo, Pedro; Correia de Sousa, Jaime; Bousquet, Jean; Almeida, António Bugalho; Giacco, Stefano R. Del; Demoly, Pascal; Haahtela, Tari

Asthma frequently occurs in association with allergic rhinitis and a combined management approach has been suggested. The Control of Allergic Rhinitis and Asthma Test (CARAT) is the first questionnaire to assess control of both diseases concurrently. However, to have an impact on healthcare it needs to be disseminated and adopted. In this paper we discuss the dissemination of CARAT in different countries and it...


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