8 documents found, page 1 of 1

Diretrizes Brasileiras de Hipertensão Arterial – 2020

Made available in DSpace on 2021-06-25T11:03:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-03-01. Added 1 bitstream(s) on 2021-07-15T14:36:02Z : No. of bitstreams: 1 S0066-782X2021000400516.pdf: 3972880 bytes, checksum: b9bdbad26f21c4bcb57e0ea9683f5e70 (MD5); Universidade Federal de Goiás; Liga de Hipertensão Arterial; Pontifícia Universidade Católica de São Paulo Faculdade de Ciências Médicas e da ...

Adrenal Insufficiency and Glucocorticoid Use During the COVID-19 Pandemic

The coronavirus disease 2019 (COVID-19) is an emerging pandemic challenge. Acute respiratory distress syndrome (ARDS) in COVID-19 is characterized by a severe cytokine storm. Patients undergoing glucocorticoid (GC) replacement therapy for adrenal insufficiency (AI) represent a highly vulnerable group that could develop severe complications due to the SARS-CoV-2 infection. In this review, we highlight the strate...

Primary malignant tumors of the adrenal glands

Malignancy must be considered in the management of adrenal lesions, including those incidentally identified on imaging studies. Adrenocortical carcinomas (ACCs) are rare tumors with an estimated annual incidence of 0.7–2 cases per year and a worldwide prevalence of 4–12 cases per million/year. However, a much higher incidence of these tumors (415 times) has been demonstrated in south and southeastern Brazil. Mo...

GLUT1 expression in pediatric adrenocortical tumors: a promising candidate to p...

Background: Discrimination between benign and malignant tumors is a challenging process in pediatric adrenocortical tumors. New insights in the metabolic profile of pediatric adrenocortical tumors may contribute to this distinction, predict prognosis, as well as identify new molecular targets for therapy. The aim of this work is to characterize the expression of the metabolism-related proteins MCT1, MCT2, MCT4,...

Expression of LIN28 and its regulatory microRNAs in adult adrenocortical cancer

Metabolic reprogramming: a new relevant pathway in adult adrenocortical tumors

Adrenocortical carcinomas (ACCs) are complex neoplasias that may present unexpected clinical behavior, being imperative to identify new biological markers that can predict patient prognosis and provide new therapeutic options. The main aim of the present study was to evaluate the prognostic value of metabolism-related key proteins in adrenocortical carcinoma. The immunohistochemical expression of MCT1, MCT2, MC...

New Insights into the Role of LIN28A and LIN28B in Adrenocortical Tumorigenesis...

Isolated familial somatotropinoma: 11Q13-LOH and gene/protein expression analys...

OBJECTIVE: Non-pituitary tumors have been reported in a subset of patients harboring germline mutations in the aryl hydrocarbon receptor-interacting protein (AIP) gene. However, no detailed investigations of non-pituitary tumors of AIP-mutated patients have been reported so far. PATIENTS: We examined a MEN1- and p53-negative mother-daughter pair with acromegaly due to somatotropinoma. Subsequently, the mother d...