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Outcomes of transcatheter aortic valve replacement in younger low-risk patients

Rocha de Almeida, António; Lima, Maria Rita; Gomes, Daniel A.; Fernandes, Renato; Oliveira, Eduardo Infante; de Araújo Gonçalves, Pedro

Publisher Copyright: 2025 Rocha de Almeida, Lima, Gomes, Fernandes, Oliveira, Gonçalves, Teles, de Sousa Almeida and Patrício.; Background and aims: Severe aortic stenosis (AS) was traditionally managed with surgical aortic valve replacement (SAVR). Transcatheter aortic valve implantation (TAVI) emerged as a less invasive alternative, initially for high-risk patients. This meta-analysis evaluates the outcomes o...


Pantoprazole-Induced Liver Injury in the Setting of Diabetic Ketoacidosis

Oliveira, Raquel; Almeida, Manuel; Lavado, Pedro; Baptista, Alexandre

N/a.; N/a.

Date: 2024   |   Origin: Acta Médica Portuguesa

Interventional cardiology in cancer patients: a position paper from the Portugu...

Menezes, Miguel Nobre; Tavares da Silva, Marta; Magalhaes, Andreia; Melica, Bruno; Toste, Júlia Cristina; Calé, Rita; Almeida, Manuel; Fiuza, Manuela

The field of Cardio-Oncology has grown significantly, especially during the last decade. While awareness of cardiotoxicity due to cancer disease and/or therapies has greatly increased, much of the attention has focused on myocardial systolic disfunction and heart failure. However, coronary and structural heart disease are also a common issue in cancer patients and encompass the full spectrum of cardiotoxicity. ...


Pantoprazole-induced liver injury in the setting of diabetic ketoacidosis

de Oliveira, Raquel; Almeida, Manuel; Lavado, Pedro; Baptista, Alexandre

Critically ill patients are at higher risk of acquired liver in-jury, given the multiple coexisting potential causes of injury.1They are also at risk of stress ulcers, and prophylaxis with proton pump inhibitors (PPIs) is common in Intensive Care Units (ICUs). A 54-year-old woman was admitted to the ICU due to diabetic ketoacidosis (DKA). On admission, she was hemo-dynamically stable, with a Glasgow Coma Scale ...


Antitumoral and antimicrobial activities of block copolymer micelles containing...

Sousa, Andreia; Santos, Joana F.; Silva, Francisco; Sousa, Sílvia A.; Leitão, Jorge H.; Matos, António P.; Pinheiro, Teresa; Silva, Rafaela A. L.

Gold(III) bisdithiolate complexes have been reported as potential antimicrobial and antitumoral agents. The complex [Au(cdc)2]− (cdc=cyanodithioimido carbonate) displayed antimicrobial and outstanding antitumor activity against the ovarian cancer cells A2780 and A2780cisR, which are sensitive and resistant to cisplatin, respectively. However, poor water solubility may hamper its clinical use. Block copolymer mi...



The solid solutions (Per)(2)[PtxAu(1-x)(mnt)(2)]; alloying para-and diamagnetic...

Matos, Manuel; Bonfait, Gregoire; Santos, Isabel C.; Afonso, Monica L.; Henriques, Rui T.; Almeida, Manuel

The alpha-(Per)(2)[M(mnt)(2)] compounds with M = Pt and Au are isostructural two-chain solids that in addition to partially oxidized conducting perylene chains also contain anionic chains that can be either paramagnetic in the case of M = Pt or diamagnetic for M = Au. The electrical transport and magnetic properties of the solid solutions (Per)(2)[Pt-x-Au(1-x)(mnt)(2)] were investigated. The incorporation of pa...


Stent for Life in Portugal : this initiative is here to stay

Pereira, Hélder; Pinto, Fausto J.; Calé, Rita; Pereira, Ernesto; Marques, Jorge; Almeida, Manuel; Mello, Sofia de; Martins, Luís Dias

Aims: Portugal has one of the lowest rates of primary percutaneous coronary intervention (p-PCI) in Western Europe. This study assessed the progress of Portuguese p-PCI performance indicators one year after Portugal joined the Stent for Life (SFL) initiative. Methods and Results: Two national surveys were carried out, each covering a period of one month: the first when Portugal joined the SFL in 2011 (Moment Ze...


Transferência e contra-transferência numa psicoterapia

Almeida, Manuel

O presente trabalho é um estudo de um caso clínico de uma jovem de dezanove anos, a Ana. Tivemos o primeiro contacto com Ana num hospital psiquiátrico de Lisboa onde estava internada. Chegou ao Hospital pela mão de dois polícias que a tinham ido buscar a casa por alegados comportamentos agressivos. Foi-lhe atribuída uma psiquiatra que nos pediu uma avaliação psicológica. Dois meses mais tarde Ana procura-nos pa...


Critérios de diagnóstico de anomalias da homeostasia da glicose da ADA e da IDF...

Rodrigues, Pedro; Esteves, Cesar; Belo, Sandra; Nogueira, Claudia; Matos, Maria; Varela, Ana; Freitas, Paula; Queirós, Joana; Correia, Flora

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