22 documents found, page 1 of 3
Exploring the Complex Ethical Challenges Associated with Living Donor Kidney Tr...
Almeida, Manuela; Machado, DomingosLiving donor kidney transplantation is regarded as the best treatment for selected patients with end ‑stage renal disease, associated with improved survival and quality of life. However, it should be recognized as a distinct medical procedure during which an organ is procured from a healthy individual for the benefit of another patient. Seven decades after the first successful procedure, ethical constraints pe...
Renal artery stenosis in living donor kidney transplantation: a rare cause of “...
Dias, Bruno Fraga; Marques, Roberto; Faria, Vitória; Domingues, Patrícia; Ribeiro, Catarina; Silvano, José; Malheiro, Jorge; Almeida, ManuelaTransplant renal artery stenosis (TRAS) is a well-recognized vascular complication after kidney transplantation, with an incidence ranging from 1% to 23%. TRAS often presents with clinical features such as refractory hypertension, de novo hypertension, allograft dysfunction, and the presence of a bruit over the graft. A rare manifestation of TRAS is flash pulmonary edema. Here, we present a case of a 37-year-ol...
Greater Impact of Living Donation Than HLA Mismatching in Short-Term Renal Allo...
Ribeiro, Bárbara; Reis Pereira, Pedro; Oliveira, João; Almeida, Manuela; Martins, La Salete; J, MalheiroIntroduction: Living donor kidney transplantation (LDKT) is accepted as first-line treatment for patients with end-stage kidney disease with advantages over deceased donor kidney transplantation (DDKT). Still, how the known detrimental effect of HLA mismatch (MM) may hamper these advantages remains unsettled. We sought to determine the effect of the degree of HLA MM, separately in deceased and living donor rena...
Association of the Calcification Score of the Abdominal Aorta, Common Iliac, an...
Ribeiro, Luís Costa; Almeida, Manuela; J, Malheiro; Silva, Filipa; Nunes-Carneiro, Diogo; Martins, La Salete; Pedroso, Sofia; Silva-Ramos, MiguelBackground: Vascular calcification is an ever-more-common finding in protocoled pre-transplant imaging in living kidney donors. We intended to explore whether a connection could be found between the Agatston calcification score, prior to kidney donation, and post-donation renal function. Methods: This is a retrospective analysis of 156 living kidney donors who underwent living donor nephrectomy between January ...
Living Donors’ Age Modifies the Impact of Pre-Donation Estimated Glomerular Fil...
Almeida, Manuela; Ribeiro, Catarina; Silvano, José; Pedroso, Sofia; Tafulo, Sandra; Martins, La Salete; Ramos, Miguel; J, MalheiroBackground: The global scarcity of organs for kidney transplants (KTs) has led to the increased acceptance of living donors (LDs) with minor abnormalities to increase the donor pool.. We sought to evaluate the effects of some of these LDs' clinical characteristics (older age, borderline renal function, hypertension, dyslipidemia, smoking, and obesity) on graft outcomes. Methods: We studied 352 recipients of LDK...
CT volumetry performs better than nuclear renography in predicting estimated re...
Almeida, Manuela; Pereira, Pedro R.; Ramos, Miguel; Nunes-Carneiro, Diogo; Mandaleno, Mariana; Silva, Filipa; Pedroso, Sofia; França, ManuelaThe evaluation of split renal function (SRF) is a critical issue in living kidney donations and can be evaluated using nuclear renography (NR) or computerized tomography (CT), with unclear comparative advantages. We conducted this retrospective study in 193 donors to examine the correlation of SRF assessed by NR and CT volumetry and compared their ability to predict remaining donor renal function at 1 year, thr...
Gender and tobacco consumption among University students
Costa, Emília; Godoy, María de los Ángeles Merino; Almeida, Manuela; Silva, Alexandra; Nave, FilipeIn 2019, an estimated 155 million people aged between 15 and 24 were smokers. It is also known that 82.6% of current smokers started smoking between 14 and 25 years old. Tobacco uses in adolescents and young adults can lead to the development of serious and potentially life-threatening health problems. The aim of the present investigation is to identify and describe the practices related to the consumption of t...
Impact of Pancreatic Autoantibodies in Pancreas Graft Survival After Pancreas-K...
Pestana, Nicole; Malheiro, Jorge; Silva, Filipa; Silva, Andreia; Ribeiro, Catarina; Pedroso, Sofia; Almeida, Manuela; Dias, LeonídioIn simultaneous pancreas-kidney transplantation (SPKT), persistence or recurrence of pancreatic autoantibodies (PAs) has been associated with pancreas graft (PG) autoimmune-driven injury. Our aim was to analyze the impact of PAs on PG survival.Methods. Between January 1, 2000, and December 31, 2017, we studied 139 patients with post-SPKT antieglutamic acid decarboxylase (GAD) autoantibody. Alloimmune (ALI) even...
Thermal Performance and Comfort Conditions Analysis of a Vernacular Palafitic T...
Fernandes, Jorge; Mateus, Ricardo; Gervásio, Helena; Silva, Sandra Monteiro; Branco, Jorge; Almeida, ManuelaThe palafitic timber constructions of the central Portuguese coastline are an example of the adaptation to site-specific conditions (climate and sand landscape morphodynamics) using the available endogenous resources. Thus, in a context of environmental awareness and climate change, it is relevant to understand their features/strategies and how they perform. This work analyses the energy performance and thermal...
Remaining kidney volume indexed to weight as a strong predictor of estimated gl...
Nunes-Carneiro, Diogo; Madanelo, Mariana; Silva, Filipa; Pestana, Nicole; Ribeiro, Catarina; Gil‐Sousa, Diogo; Martins, La Salete; Almeida, ManuelaThe donors' estimated glomerular filtration rate (eGFR) after living nephrectomy has been a concern, particularly in donors with smaller kindeys. Therefore, we developed this retrospective observational study in 195 donors to determine the ability remaining kidney volume indexed to weight (RKV/W) to predict eGFR at 1 year through multivariate linear regression and to explore this relationship between annual eGF...