38 documents found, page 1 of 4
Cebranopadol, a first-in-class investigational opioid: Insights from preliminar...
Almeida, Margarida; Diogo , Beatriz; Rocha , Joana; Dinis-Oliveira , Ricardo Jorge; Cunha , Andrea; Faria , Juliana; Barbosa, JoanaBackground: Cebranopadol, a promising opioid analgesic undergoing phase III trials, was developed for the treatment of acute and chronic moderate-to-severe pain. Because it is a non-selective ligand acting at more than one member of the opioid receptor family, combining a dual agonist action on mu-, delta-, and kappa-opioid receptors (MOR, DOR, and KOR) and nociceptin/orphanin FQ peptide (NOP) receptors, it has...
Polysaccharide-Based Carriers for Pulmonary Insulin Delivery: The Potential of ...
Valente, Sara A.; Lopes, Guido R.; Ferreira, Isabel; Galrinho, Miguel F.; Almeida, Margarida; Ferreira, Paula; Cruz, Maria T.; Coimbra, Manuel A.Non-invasive routes for insulin delivery are emerging as alternatives to currently painful subcutaneous injections. For pulmonary delivery, formulations may be in powdered particle form, using carriers such as polysaccharides to stabilise the active principle. Roasted coffee beans and spent coffee grounds (SCG) are rich in polysaccharides, namely galactomannans and arabinogalactans. In this work, the polysaccha...
eHealthResp, a Digital Intervention to Improve Antibiotic Prescribing in Respir...
Silva, Tânia; Estrela, Marta; Magalhães, Sandra; Simões, Catarina; Cachim, Afonso; Costa, Tainá; Crexinski, Gabriella; Almeida, MargaridaThe emergence of antibiotic resistance (ABR) is one of the most serious public health threats worldwide. The inappropriate use of antibiotics is considered the main determinant for the increase and development of ABR, contributing to a greater risk of therapeutic ineffectiveness, particularly within primary care context. Therefore, this pilot study aims to raise awareness and promote an adequate antibiotic use ...
Improving Pharmacists Awareness of Inadequate Antibiotic Use for URTIs through ...
Magalhães, Sandra; Estrela, Marta; Silva, Tânia; Costa, Tainá; Crexinski, Gabriella; Simões, Catarina; Almeida, Margarida; Figueiras, AdolfoThe inadequate use of antibiotics led to the development of multi-resistant bacteria that are now causing millions of deaths worldwide. Since most antibiotics are prescribed/dispensed to treat respiratory tract infections, it is important to raise awareness among health professionals to optimize antibiotic use, especially within the primary care context. Thus, this pilot study aimed to evaluate pharmacists' fee...
Guidelines for Management of Postoperative Hypoparathyroidism
Chaves, Catarina; Martinho, Mariana; Cunha, Filipe; Garrido, Susana; Vieira, Margarida; Almeida, MargaridaThe regulation of the blood calcium level is achieved through parathyroid hormone (PTH) and 1,25 dihydroxyvitamin D, the active metabolite of vitamin D. Hypocalcemia may be associated with a spectrum of clinical manifestations, from mild to severe symptoms, which can endanger the patient´s life. Most cases of acute hypocalcemia occur in the context of hypoparathyroidism secondary to cervical surgery, due to the...
Meaning in life, meaning-making and posttraumatic growth in cancer patients: Sy...
Almeida, Margarida; Ramos, Catarina; Maciel, Laura; Basto-Pereira, Miguel; Leal, I.Introduction: The purpose of this systematic review and meta-analysis is to assess the association between meaning in life (MiL), meaning-making and posttraumatic growth (PTG) in the context of cancer. Methods: A systematic search was conducted in eighteen electronic databases. The screening and selection process followed the PRISMA guidelines. For the purpose of the meta-analysis, the correlation coefficients ...
Usability evaluation of a community-led innovation mobile app
Branco, André Castello; Sacramento, Eveline R.; Oliveira, Eliza; Tymoshchuk, Oksana; Antunes, Maria; Almeida, Margarida; Pedro, Luís; Ramos, FernandoDigital media can facilitate collaborative processes among local agents, value endogenous resources, and promote assets associated with territory. This article presents the results of a study concerning the development and validation of a mobile app for promoting the relationship among agents of the Portuguese Centro region’s communities/entities. This paper focuses on the results of a heuristic evaluation of t...
Promoting community-based networks through digital media
Oliveira, Eliza; Carvalho, Daniel; Sacramento, Eveline; Branco, André; Antunes, Maria João; Pedro, Luís; Tymoshchuck, Oksana; Almeida, MargaridaDigital media can provide an essential contribution to the development of local communities by creating digital environments that facilitate the sharing of information, dissemination of knowledge, and construction of organizational learning. Digital media can also promote interaction and collaboration processes among different regional agents, fostering a continuous flow of territorial-based innovation. The stu...
Meaning in life, meaning-making and posttraumatic growth in cancer patients : s...
Almeida, Margarida; Ramos, Catarina; Maciel, Laura; Basto-Pereira, Miguel; Leal, IsabelIntroduction: The purpose of this systematic review and meta-analysis is to assess the association between meaning in life (MiL), meaning-making and posttraumatic growth (PTG) in the context of cancer. Methods: A systematic search was conducted in eighteen electronic databases. The screening and selection process followed the PRISMA guidelines. For the purpose of the meta-analysis, the correlation coefficients ...
Jovens Solistas da Metropolitana
Ferreira, Beatriz; Marques, Inês; Félix, Edney; Almeida, Margarida; Herculano, Cristiana; Pinto, Ana Catarina; Ferreirinho, Ana; Ferreira, InêsBrochura de sala do concerto realizado pelos Jovens Solistas da Metropolitana a 3 de Junho de 2021 no MUSEU DO ORIENTE em Lisboa no âmbito da Temporada 2020/2021 da Metropolitana. O programa do concerto foi preenchido com obras de Ravel, Tull, Schostakovich e Debussy. Desenvolvendo uma ponte pedagógica inédita entre a prática e o ensino musical, a ANSO é a única escola do país que forma maestros, instrumentista...