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Development of a dry powder insufflation device with application in in vitro ce...

Pontes, Jorge Filipe; Diogo, Hermínio P.; Conceição, Eusébio; Almeida, Maria P.; Borges dos Santos, Rui M.; Grenha, Ana

Research on pharmaceutical dry powders has been increasing worldwide, along with increased therapeutic strategies for an application through the pulmonary or the nasal routes. In vitro methodologies and tests that mimic the respiratory environment and the process of inhalation itself are, thus, essential. The literature frequently reports cell-based in vitro assays that involve testing the dry powders in suspen...


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