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Tau deletion prevents stress-induced dendritic atrophy in prefrontal cortex: ro...
Lopes, Sofia Oliveira; Teplytska, Larysa; Silva, João Luís Vaz Lima da; Dioli, Chrysoula; Trindade, Rita; Morais, Mónica; Webhofer, ChristianTau protein in dendrites and synapses has been recently implicated in synaptic degeneration and neuronal malfunction. Chronic stress, awell-known inducer of neuronal/synaptic atrophy, triggers hyperphosphorylation of Tau protein and cognitive deficits. However, the cause–effect relationship between these events remains to be established. To test the involvement of Tau in stress-induced impairments of cognition,...
Date: 2017
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Origin: RepositóriUM - Universidade do Minho