19 documents found, page 1 of 2
Older-to-Older Living Kidney Transplantation: A New Paradigm
Figueiredo,Cátia Raquel; Sousa,Círia; Ventura,Sofia; Cruz,Gonçalo; Almeida,Manuela; Silvano,José; Malheiro,Jorge; Pedroso,Sofia; Martins,La SaleteABSTRACT Older to older living kidney transplantation is an acceptable alternative to avoid dialysis, improve quality of life and maintain favorable long-term outcomes of patients with end-stage kidney disease. However, the management of these patients is complex and the acceptance of older donors and recipients to kidney transplantation remains controversial. The older recipients usually have several comorbidi...
Late Onset of Pneumocystis jirovecii Pneumonia in Kidney Transplant: How Long i...
Sousa,Círia Leandra Martins de; Figueiredo,Cátia Raquel; Ventura,Sofia; Almeida,Manuela; Martins,La SaleteABSTRACT Pneumocystis jirovecii (PJ) opportunistic infections occur in immunocompromised patients impacting significantly hospitalizations and mortality. Trimethoprim-sulfamethoxazole (TMP-SMX) is universally used as prophylaxis of Pneumocystis jirovecii pneumonia (PJP) and therefore, this infection is rare condition in solid organ transplant (SOT) recipients. We present a case of a 46-years-old male, who recei...
ABO-incompatible living donor kidney transplantation in Portugal
Ribeiro,Catarina Isabel; Silva,Natália; Malheiro,Jorge; Almeida,Manuela; Pedroso,Sofia; La Salete Martins,Maria; Dias,Leonídio; Henriques,António CastroIntroduction: ABO incompatibility was considered a barrier to kidney transplant. However, the shortage of available organs for transplantation and the excellent long-term results further establish ABO-incompatible (ABOi) as a safe and effective therapeutic strategy. The aim of the present study was to evaluate the outcomes of ABOi transplantation in terms of graft survival and function, rejection episodes and i...
Rituximab-induced hypersensitivity pneumonitis in a kidney transplant patient
Silva,Natália; Ribeiro,Catarina Isabel; Almeida,Manuela; Malheiro,Jorge; Pedroso,Sofia; Martins,Maria La Salete; Dias,Leonídio; Henriques,António CastroRituximab (RTX) is a chimeric anti-CD20 monoclonal antibody that has been associated with delayed pulmonary toxicity. In patients receiving RTX, hypersensitivity pneumonitis, although rare, should be considered in the appropriate clinical and radiographic setting. The authors present a case of hypersensitivity pneumonitis associated with a single dose of RTX treatment in a kidney transplanted patient with acute...
TYROSINEMIA TYPE III: A CASE REPORT OF SIBLINGS AND LITERATURE REVIEW
Barroso,Fábio; Correia,Joana; Bandeira,Anabela; Carmona,Carla; Vilarinho,Laura; Almeida,Manuela; Rocha,Júlio César; Martins,EsmeraldaABSTRACT Objective: Tyrosinemia type III (HT III) is the rarest form of tyrosinemia, and the full clinical spectrum of this disorder is still unknown. The neurological involvement varies, including intellectual impairment and attention deficit disorder with hyperactivity (ADHD). We report the case of two siblings diagnosed with HT III at different ages. Case description: The index case was diagnosed by newborn ...
Refractory ascites and graft dysfunction in early renal transplantation
Eusébio,Catarina Pereira; Correia,Sofia; Silva,Filipa; Almeida,Manuela; Pedroso,Sofia; Martins,La Salete; Diais,Leonídio; Queirós,JoséAbstract The occurrence of ascites after Renal Transplant (RT) is infrequent, and may be a consequence of surgical or medical complications. Case report: 61 year-old, male, history of arterial hypertension, tongue carcinoma and alcoholic habits 12-20g/day. He had chronic kidney disease secondary to autosomal dominant polycystic kidney disease, without hepatic polycystic disease. He underwent cadaver donor RT in...
Severe passenger lymphocyte syndrome associated to Rh antibodies after donor li...
Antunes,Marika Bini; Malheiro,Jorge; Dias,Leonidio; Martins,La Salete; Pedroso,Sofia; Almeida,Manuela; Henriques,Antonio Castro; Amil,MargaridaThe passenger lymphocyte syndrome may cause hemolytic anemia after bone marrow and solid organ transplantation when there is minor erythrocyte antigen incompatibility in the donor/recipient pair. Anemia is usually self-limiting, frequently related to ABO antibodies and rarely to Rh mismatches. We report a rare case of passenger B lymphocyte syndrome mediated by Rh antibodies occurring after a donor living renal...
Implications for patients waiting for a kidney transplant of using the calculat...
Magriço,Rita; Malheiro,Jorge; Tafulo,Sandra; Pedroso,Sofia; Almeida,Manuela; ,La Salete; Dias,Leonídio; Castro-Henriques,António; Cabrita,AntónioIntroduction: Kidney transplant improves survival even in highly-sensitized(HS) patients. To overcome their disadvantage in accessing transplantation, those with high Complement Dependent Cytotoxic PRA (CDC-PRA) receive additional points during allocation. Whether this strategy reaches all HS patients and how long they wait for a transplant is largely undetermined. Methods: Patients on our units active wait-li...
Malignancy after renal transplantation: a single-centre experience
Vieira,Pedro; Barreto,Patrícia; Pedroso,Sofia; Almeida,Manuela; Martins,La Salete; Dias,Leonídio; Henriques,António Castro; Cabrita,AntónioIntroduction: Malignancy management in renal transplant recipients is becoming a major factor affecting long-term patient survival. Thus, we intended to evaluate both incidence and prognosis of malignant diseases following renal transplantation at a single centre in Portugal. Methods: We studied retrospectively the 2,358 patients who underwent kidney transplantation (KT) between 1983 and 2014. Apart from descri...
BK virus nephropathy in kidney transplantation: A literature review following a...
Barreto,Patrícia; Almeida,Manuela; Dias,Leonídio; Vieira,Pedro; Pedroso,Sofia; Martins,La Salete; Henriques,António Castro; Cabrita,AntónioOver the last 15 years, better immunosuppressive drugs have decreased acute rejection rates in kidney transplantation but have also led to an increase in the incidence and impact of BK virus nephropathy. The authors report the case of a 62--year-old man submitted to a renal transplant of a deceased donor with an immunosuppression regimen free of rabbit anti -thymocyte globulin and tacrolimus, in whom BK nephrop...