9 documents found, page 1 of 1
Can essential oils effectively control skin bacteria?: Unveiling their powerful...
Lopes, Ana I.; Oliveira, Claudia S.; Pintado, Manuela E.; Tavaria, Freni K.Skin-associated bacteria play a significant role in various dermatological conditions. Essential oils (EOs), known for their broad-spectrum antimicrobial properties, have emerged as promising alternatives to conventional treatments for bacterial skin infections. However, studies on the potential of EOs for treating these infections have largely centered on Staphylococcus aureus. As such, this study evaluated th...
Molecules in motion: unravelling the dynamics of vascularization control in tis...
Rodrigues, Francisco A. P.; Oliveira, Claudia S.; Sá, Simone C.; Tavaria, Freni K.; Lee, Sang Jin; Oliveira, Ana L.; Costa, João B.Significant progress has been made in tissue engineering (TE), aiming at providing personalized solutions and overcoming the current limitations of traditional tissue and organ transplantation. 3D bioprinting has emerged as a transformative technology in the field, able to mimic key properties of the natural architecture of the native tissues. However, most successes in the area are still limited to avascular o...
The therapeutic potential of hematopoietic stem cells in bone regeneration
Oliveira, Claudia S.; Carreira, Mariana; Correia, Clara R.; Mano, João F.The repair process of bone fractures is a complex biological mechanism requiring the recruitment and in situ functionality of stem/stromal cells from the bone marrow (BM). BM mesenchymal stem/stromal cells have been widely explored in multiple bone tissue engineering applications, whereas the use of hematopoietic stem cells (HSCs) has been poorly investigated in this context. A reasonable explanation is the fac...
Intranasal drug delivery for treatment of Alzheimer's disease
Fonseca, Leonor Cancela; Lopes, Joao; Vieira, Joao; Viegas, Claudia; Oliveira, Claudia S.; Hartmann, Rafael P.; Fonte, PedroThe Alzheimer's disease is a neurodegenerative condition with severe consequences interfering with patient quality of life. It is characterized as a progressive and irreversible brain disorder hampering memory and thinking, affecting the capacity to perform daily tasks leading to physical and cognitive incapacitation. The conventional treatment occurs by the oral route, but it presents relevant drawbacks such a...
Differences between the activity of the masticatory muscles of adults with cere...
Matsui, Miriam Yumi [UNESP]; Giannasi, Lilian Chrystiane [UNESP]; Batista, Sandra Regina Freitas [UNESP]; Amorim, Jose Benedito Oliveira [UNESP]Made available in DSpace on 2018-12-11T17:05:51Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-01-01; Objective The aim of the present study was to compare the electromyographic activity of masticatory muscles of adult patients with different degrees of oral motor impairment (cerebral palsy) with the electromyographic activity of healthy individuals in a control group. Electromyographic activity was com...
Observational study on efficacy of negative expiratory pressure test proposed a...
Hirata, Raquel P.; Aguiar, Isabella C.; Nacif, Sergio R.; Giannasi, Lilian C. [UNESP]; Leitao Filho, Fernando S. S.; Santos, Israel R.Made available in DSpace on 2013-08-12T18:40:19Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-01-01; Made available in DSpace on 2013-09-30T19:13:25Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-01-01; Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-20T15:31:06Z No. of bitstreams: 0; Made available in DSpace on 2014-05-20T15:31:06Z (GMT). No. of bitstreams:...
Static balance and function in children with cerebral palsy submitted to neurom...
Kazon, Soraia; Grecco, Luanda A. C.; Pasini, Hugo; Correa, Joao C. F.; Christovao, Thaluanna C. L.; Camillo de Carvalho, Paulo de TarsoMade available in DSpace on 2013-08-28T14:14:30Z (GMT). No. of bitstreams: 1 WOS000306956800001.pdf: 238081 bytes, checksum: f42490f2c352458c860cc3c71fae7fed (MD5); Made available in DSpace on 2013-09-30T19:23:25Z (GMT). No. of bitstreams: 2 WOS000306956800001.pdf: 238081 bytes, checksum: f42490f2c352458c860cc3c71fae7fed (MD5) WOS000306956800001.pdf.txt: 30273 bytes, checksum: 1cab9b402bd0bc38881b43da457a2525 (...
Non-native states of cardosin A induced by acetonitrile: Activity modulation vi...
Oliveira, Claudia S.; Sarmento, A. Cristina; Pereira, Anabela; Correia, Isabel; Pessoa, Joao Costa; Esteves, Valdemar I.; Fonseca, Henrique M. A. C.Cardosin A (EC: 3.4.23) is an enzyme containing two polypeptide chains, purified from pistils of Cynara cardunculus L., a cardoon, used for milk clotting in cheese making. It is amemberof the aspartic proteinases (APs), like pepsin and HIV-proteinase that are composed by two symmetric units comprising the active site. Cardosin A is thought to be involved in many cellular events such as in pollen–pistil interact...
Thermostability of cardosin A from Cynara cardunculus L.
Pina, David G.; Oliveira, Claudia S.; Sarmento, Ana C.; Barros, Marlene; Pires, Euclides; Zhadan, Galina G.; Villar, Enrique; Gavilanes, FranciscoThe structural stability of cardosin A, a plant aspartic proteinase (AP) from Cynara cardunculus L., has been investigated by high-sensitivity differential scanning calorimetry, intrinsic fluorescence and circular dichroism spectroscopy, and enzymatic activity assays. Even though the thermal denaturation of cardosin A is partially irreversible, valid thermodynamic data can be obtained within a wide pH region. A...