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Cardiovascular effects of relaxin-2: therapeutic potential and future perspectives

Almeida-Pinto, N; Dschietzig, TB; Brás-Silva C; Adao, R

The hormone relaxin-2 has emerged as a promising player in regulating the physiology of the cardiovascular system. Through binding to the relaxin family peptide receptor 1 (RXFP1), this hormone elicits multiple physiological responses including vasodilation induction, reduction of inflammation and oxidative stress, and angiogenesis stimulation. The role of relaxin-2, or its recombinant human form known as serel...

Date: 2023   |   Origin: Repositório Aberto da Universidade do Porto
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