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The Renal and Systemic Impact of Rituximabin Patients with Refractory Systemic ...

Almiro e Castro, Pedro; Oliveira, Nuno Afonso; Pinto, Helena; Alves, Rui

Lupus nephritis (LN), a severe complication of systemic lupus erythematosus (SLE), worsens the renal and vital prognosis for up to 50% of SLE patients. Standard treatment involves corticosteroids with cyclophosphamide (CyP) or mycophenolate mofetil (MMF), yet the refractory nature of some cases necessitates alternative therapies. Rituximab (RTX), an anti-CD20 monoclonal antibody, has shown potential in SLE by t...


The importance of a Peritoneal Dialysis-first policy in long term outcomes

Correia, Ana Luisa; Almiro e Castro, Pedro; Mira, Filipe; Cerqueira, Sofia; Guedes Marques, Maria; Maia, Pedro; Alves, Rui

Introduction: A significant part of peritoneal dialysis (PD) patients begins renal replacement therapy (RRT) through hemodialysis (HD) before transitioning to PD. We aim to evaluate the impact of an initial period on HD before transitioning to PD on the outcomes. Material and Methods: We conducted a retrospective cohort study including the prevalent PD patients between January 2017 and December 2019. Demographi...


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