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Adiponectin, Leptin, and IGF-1 are useful diagnostic and stratification biomark...

Marques, Vanda; Afonso, Marta; Bierig, Nina; Duarte-Ramos, Filipa; Santos-Laso, Álvaro; Jimenez-Agüero, Raul; Eizaguirre, Emma; Bujanda, Luis

Background: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease where liver biopsy remains the gold standard for diagnosis. Here we aimed to evaluate the role of circulating adiponectin, leptin, and insulin-like growth factor 1 (IGF-1) levels as non-invasive NAFLD biomarkers and assess their correlation with the metabolome. Materials and Methods: Leptin, adiponectin, and IGF-1 seru...


Sinonasal adenoid cystic carcinoma

Uceda, Leonor; Alonso, Cristina; Pavon, Maria; Ortiz, Francisco; Perez, Sofia

Sinonasal adenoid cycstic carcinoma is an uncommon tumour accounting for 10% of malignant tumours in the sinonasal zone. It is usually located in the maxillary sinus and is characterized by slow growth and capacity for perineural spread, which results in a high risk of recurrence and metastasis in other parts of the body. Today the most widely applied treatment for this carcinoma is surgical removal followed by...


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