4 documents found, page 1 of 1
Antimicrobial cyclodextrin-assisted electrospun fibers loaded with carvacrol, c...
Gonzalez-Prada, I; Anabela Borges; Santos-Torres, B; Magariños, B; Simoes, M; Concheiro, A; Alvarez-Lorenzo, C; Simões MThis work aimed to explore an alternative to the use of antibiotics for prevention and treatment of wounds infection caused by two common bacterial pathogens Staphylococcus aureus and Pseudomonas aeruginosa. For this purpose, three different essential oil components (EOCs), namely carvacrol, citronellol and cinnamic acid, were loaded into electrospun fibers of poly-epsilon-caprolactone (PCL) aided by alpha-cycl...
A Pathway From Porous Particle Technology Toward Tailoring Aerogels for Pulmona...
Duong, T; López-Iglesias, C; Szewczyk, PK; Stachewicz, U; Barros, JAR; Alvarez-Lorenzo, C; Alnaief, M; García-González, CAPulmonary drug delivery has recognized benefits for both local and systemic treatments. Dry powder inhalers (DPIs) are convenient, portable and environmentally friendly devices, becoming an optimal choice for patients. The tailoring of novel formulations for DPIs, namely in the form of porous particles, is stimulating in the pharmaceutical research area to improve delivery efficiency. Suitable powder technologi...
Lidocaine-loaded solid lipid microparticles (SLMPS) produced from gas-saturated...
López-Iglesias, C; Quílez, C; Barros, JAR; Velasco, D; Alvarez-Lorenzo, C; Jorcano, JL; Monteiro, FJ; García-González, CAThe delivery of bioactive agents using active wound dressings for the management of pain and infections offers improved performances in the treatment of wound complications. In this work, solid lipid microparticles (SLMPs) loaded with lidocaine hydrochloride (LID) were processed and the formulation was evaluated regarding its ability to deliver the drug at the wound site and through the skin barrier. The SLMPs ...
Jet cutting technique for the production of chitosan aerogel microparticles loa...
López-Iglesias, C; Barros, JAR; Ardao, I; Gurikov, P; Monteiro, FJ; Smirnova, I; Alvarez-Lorenzo, C; García-González, CABiopolymer-based aerogels can be obtained by supercritical drying of wet gels and endowed with outstanding properties for biomedical applications. Namely, polysaccharide-based aerogels in the form of microparticles are of special interest for wound treatment and can also be loaded with bioactive agents to improve the healing process. However, the production of the precursor gel may be limited by the viscosity o...