6 documents found, page 1 of 1
Scanning the horizon
Sousa, Ronaldo; Ferreira, Verónica; Costas, Susana; Alves, Celso; Anastácio, Pedro; Chaínho, Paula; Costa, Pedro A.; Duarte, Sofia; Feio, Maria JoãoFunding Information: Financial support was provided by the Portuguese Foundation for Science and Technology (FCT) through individual contracts to F. Ribeiro (CEEC/0482/2020), C. Alves (doi.org/10.54499/CEECINST/00060/2021/CP2902/CT0004), J. Padilha (CEECIND/CP2841/CT0002), S. Costas (https://doi.org/10.54499/2021.04286.CEECIND/CP1672/CT0001 and CEECINSTLA/00018/2022), M. J. Feio (https://doi.org/10.54499/2021.0...
Lanthanide-Based Organic Salts
Forte, Andreia; Gago, Sandra; Alves, Celso; Silva, Joana; Alves, Joana; Pedrosa, Rui; Laia, César A. T.; Marrucho, Isabel M.; Branco, Luís C.The formulation of magnetic ionic liquids (MILs) or organic salts based on lanthanides as anions has been explored. In this work, a set of choline-family-based salts, and two other, different cation families, were combined with Gadolinium(III) and Terbium(III) anions. Synthetic methodologies were previously optimized, and all organic salts were obtained as solids with melting temperatures higher than 100 °C. Th...
Unravelling the Dermatological Potential of the Brown Seaweed Carpomitra costata
Susano, Patrícia; Silva, Joana; Alves, Celso; Martins, Alice; Gaspar, Helena; Pinteus, Susete; Mouga, Teresa; Goettert, Márcia Ines; Petrovski, ŽeljkoUID/04292/2020 InSAICT-PAC/0019/2015-LISBOA-01-0145-FEDER-016405 POCI-01-0145-FEDER-029250; The ever-increasing interest in keeping a young appearance and healthy skin has leveraged the skincare industry. This, coupled together with the increased concern regarding the safety of synthetic products, has boosted the demand for new and safer natural ingredients. Accordingly, the aim of this study was to evaluate th...
Boosting antimicrobial activity of ciprofloxacin by functionalization of mesopo...
Mora, Blanca de Juan; Filipe, Luís; Forte, Andreia; Santos, Miguel M.; Alves, Celso; Teodoro, Fernando; Pedrosa, Rui; Carrott, Manuela RibeiroUID/MAR/04292/2020 PEst-C/LA0006/2013 RECI/BBBBQB/0230/2012 MAR-02.01.01-FEAMP-0042–INOVA4AQUA 022161; Mesoporous silica nanoparticles (MSNs) are very promising nanomaterials for treating bacterial infections when combined with pharmaceutical drugs. Herein, we report the preparation of two nanomaterials based on the immobilization of ciprofloxacin in mesoporous silica nanoparticles, either as the counter-ion of...
Antimicrobial activities of highly bioavailable organic salts and ionic liquids...
Santos, Miguel M.; Alves, Celso; Silva, Joana; Florindo, Catarina; Costa, Alexandra; Petrovski, Željko; Marrucho, Isabel M.; Pedrosa, RuiUIDB/50006/2020 PTDC/QUI-QOR/32406/2017 PEst-C/LA0006/2013 RECI/BBBBQB/0230/2012; As the development of novel antibiotics has been at a halt for several decades, chemically enhancing existing drugs is a very promising approach to drug development. Herein, we report the preparation of twelve organic salts and ionic liquids (OSILs) from ciprofloxacin and norfloxacin as anions with enhanced antimicrobial activity....
Highlighting the biological potential of the brown seaweed fucus spiralis for s...
Freitas, Rafaela; Martins, Alice; Silva, Joana; Alves, Celso; Pinteus, Susete; Alves, Joana; Teodoro, Fernando; Ribeiro, Helena MargaridaUID/MAR/04292/2020 PTDC/MAR-BIO/6149/2014 POCI-01-0145-FEDER-016791 SAICTPAC/0019/2015-LISBOA-01-0145-FEDER-016405 PTDC/BIA-OUT/29250/2017 POCI-01-0145-FEDER-029250 Centro-01-0145-FEDER-000018; Skin aging is a biological process influenced by intrinsic and extrinsic factors. The last ones, mainly exposure to UV radiation, increases reactive oxygen species (ROS) production leading to a loss of extracellular matr...