38 documents found, page 1 of 4
Antineoplastic drugs in healthcare settings: Occupational exposure and risk gra...
Portilha-Cunha, MF; Norton, P; Alves, A; Ribeiro, ARL; Silva, AMT; Santos, MSFAntineoplastic drugs (ADs) are hazardous medicinal products highlighted in the EU strategic framework on health and safety at work 2021–2027. To minimize workers' chronic exposure in oncologic settings, regular monitoring programs for these drugs are crucial and mandatory in the EU (Directive 2004/37/EC). No surveillance exists in Portugal, thus we intended to assess environmental contamination and to perform o...
Development and validation of a multicompound LLE–LC–MS/MS method for biomonito...
Portilha-Cunha, MF; Alves, A; Ribeiro, ARL; Silva, AMT; Norton, P; Santos, MSFAntineoplastic drugs are carcinogens, mutagens, or teratogenic substances, which can pose serious risks to professionals. Concerns about chronic exposure to these hazardous medicinal products (HMPs) have led to their prominence in the EU strategic framework on health and safety at work 2021–2027. To estimate and mitigate human exposure to HMPs, regular monitoring programs and, consequently, reliable, sensitive,...
Antineoplastic drugs in urban wastewater: Occurrence, nanofiltration treatment ...
Gouveia, TIA; Cristóvão, MB; Pereira, VJ; Crespo, JG; Alves, A; Ribeiro, AR; Silva, A; Santos, MSFAntineoplastic drugs are pharmaceuticals that have been raising concerns among the scientific community due to: (i) their increasing prescription in the fight against the disease of the twentieth century (cancer); (ii) their recalcitrance to conventional wastewater treatments; (iii) their poor environmental biodegradability; and (iv) their potential risk to any eukaryotic organism. This emerges the urgency in f...
Theoretical rejection of fifty-four antineoplastic drugs by different nanofiltr...
Gouveia, TIA; Alves, A; Santos, MSFThe rise of nanofiltration technologies holds great promise for creating more effective and affordable techniques aiming to remove undesirable pollutants from wastewaters. Despite nanofiltration's promising potential in removing antineoplastic drugs from liquid matrices, the limited information on this topic makes it important to estimate the rejection rates for a larger number of compounds, particularly the em...
Nanofiltration combined with ozone-based processes for the removal of antineopl...
Gouveia, TIA; Gorito, AM; Cristóvão, MB; Pereira, VJ; Crespo, J; Alves, A; Pereira, MFR; Ribeiro, ARL; Silva, AMT; Santos, MSFOver the past years, there has been an increasing concern about the occurrence of antineoplastic drugs in water bodies. The incomplete removal of these pharmaceuticals from wastewaters has been confirmed by several scientists, making it urgent to find a reliable technique or a combination of techniques capable to produce clean and safe water. In this work, the combination of nanofiltration and ozone (O3)-based ...
Adsorption Technologies for the Removal of Cytostatics in Water: A Review
Garcia-Costa, AL; Gouveia, TIA; Alves, A; Santos, MSFOne of the most common treatments for cancer disease requires the administration of cytostatics, which are very effective drugs in the elimination of cancerous cells, but are toxic for healthy tissues. After being administered to patients, they are excreted and frequently reach natural water bodies, due to their poor degradation in wastewater treatment plants (WWTPs), posing a global threat to the environment a...
Saltquanti - development of a new portable device to analyse salt content in food
Bernardo, F; Moreira, JL; Gonçalves, C; Pena, MJ; Pinho, Olívia; Martins, R; Alves, AExcessive salt intake is a growing concern in society, impacting on a number of serious clinical conditions, such as the development of hypertension and increased mortality/morbidity caused by cardiovascular diseases. The urgent need to introduce in situ assessment of the salt content of processed foods led to the development of SALTQUANTI, a portable device developed and patented by a consortium promoted by th...
COVID-19 Related Hospital Re-organization and Trends in Tuberculosis Diagnosis ...
Alves, A; Aguiar, A; Migliori, GB; Duarte, R[No abstract available]
Feasibility and Acceptability of an Asthma App to Monitor Medication Adherence:...
Jácome, C; Almeida, R; Pereira, AM; Amaral, R; Mendes, S; Alves-Correia, M; Vidal, C; López Freire, S; Méndez Brea, P; Araújo, L; Couto, MBackground: Poor medication adherence is a major challenge in asthma, and objective assessment of inhaler adherence is needed. The InspirerMundi app aims to monitor adherence while providing a positive experience through gamification and social support. Objective: This study aimed to evaluate the feasibility and acceptability of the InspirerMundi app to monitor medication adherence in adolescents and adults wit...
Monitoring Adherence to Asthma Inhalers Using the InspirerMundi App: Analysis o...
Jácome, C; Almeida, R; Pereira, AM; Amaral, R; Vieira-Marques, P; Mendes, S; Alves-Correia, M; Ferreira, JA; Lopes, I; Gomes, J; Araújo, L; Couto, MBackground: Poor medication adherence is a major challenge in asthma and objective assessment of inhaler adherence is needed. InspirerMundi app aims to monitor inhaler adherence while turning it into a positive experience through gamification and social support. Objective: We assessed the medium-term feasibility of the InspirerMundi app to monitor inhaler adherence in real-world patients with persistent asthma ...