Abstract: Objective: Suicide represents 800.000 annual deaths, worldwide, and three daily deaths in Portugal. Suicide prevention in a clinical context involves intervening in risk factors such as suicidal ideation. However, this prevention is lacking, given that, globally, 40% of individuals who died by suicide visited emergency services in the previous year. Healthcare professionals face anxiety and difficulti...
Extractive fermentation is an integrated process that uses aqueous biphasic systems to combine the production and primary purification procedures into a single step. With this concept, the main goal of this work was to design a bioprocess that integrates laccase production and purification using a genetically engineered yeast (Pichia pastoris), creating a competitive and sustainable process. Successful expressi...
Peptidyl-prolyl cis-trans isomerase C (Ppic) is expressed in several bone marrow (BM) hematopoietic progenitors and in T-cell precursors. Since the expression profile of Ppic in the hematoimmune system was suggestive that it could play a role in hematopoiesis and/or T lymphocyte differentiation, we sought to test that hypothesis in vivo. Specifically, we generated a Ppic-deficient mouse model by targeting the e...
Peptidyl-prolyl cis-trans isomerase C (Ppic) is expressed in several bone marrow (BM) hematopoietic progenitors and in T-cell precursors. Since the expression profile of Ppic in the hematoimmune system was suggestive that it could play a role in hematopoiesis and/or T lymphocyte differentiation, we sought to test that hypothesis in vivo. Specifically, we generated a Ppic-deficient mouse model by targeting the e...
No presente relatório, encontra-se descrito o leque de práticas executadas no decorrer dos dois meses e meio de estágio. Ergomoments foi a entidade escolhida para a realização do estágio de fim de licenciatura. O facto de se encontrar dividida em dois setores, o setor meramente comercial e o setor organizador de eventos, permitiu que o estágio realizado nesta empresa fosse completo e diversificado a nível de at...
Quantum computing has the potential to provide solutions to many problems which are challenging or out of reach of classical computers. There are several problems in rendering which are amenable to being solved in quantum computers, but these have yet to be demonstrated in practice. This work takes a first step in applying quantum computing to one of the most fundamental operations in rendering: ray casting. Th...
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Last decade is characterized by different types of crises and shocs in the socioeconomic systems, creating a turbulent context and calling for a better understanding of what the dynamic perspective of change is. For countries, regions and cities a better understanding of governance urges and calls for action.