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Transepiphyseal Fracture­‐Dislocation of the Hip inan Adolescent: A Rare Clinic...

Moreira, Andreia G.; Balacó, Inês; Cabral, João; Alves, Cristina

Hip fracture‐dislocations in children and adolescents are rare and severe injuries. Surgical treatment is urgent and, even with adequate and timely treatment, the complication rate is high. The most common complication is osteonecrosis of the femoral head and the main risk factors include fracture type and displacement. A 13‐year‐old boy presented after a high‐energy trauma, having sustained a fracture‐dislocat...


Pediatric Compartment Syndrome

Viegas, Rui; Viegas, Rui; Carvalho, Marcos; Cabral, João; Sá Cardoso, Pedro; Tarquini, Oliana; Balacó, Inês; Ling, Tah Pu; Alves, Cristina

Introduction: Compartment syndrome (CS) is an orthopedic emergency. Diagnosis is particularly difficult in children because of the challenges inherent to communication and clinical examination. This paper aims to present a pediatric case series of CS and to analyze its etiology, diagnosis, treatment and complications as well as to assess the quality of life of the patients at least 1 year after the event. Metho...


Mechanical Expandable Tumoral Prosthesis Lengthening Mechanism Collapse: Salvag...

Rodrigues, Sónia; Balacó, Inês; Alves, Cristina; Matos, Gabriel

We describe a clinical case of a patient with osteosarcoma, who underwent resection and reconstruction with an expandable prosthesis, mechanical failure of the lengthening device and sudden dysmetria. Girl, 8 years old, with distal metadiaphyseal osteosarcoma of the left femur. She underwent a 14cm resection and reconstruction with an expandable prosthesis. Mechanical lengthening without complications, totaling...


Modelling therapeutic response in asthmatic adults: a previous exploratory anal...

Alves, Cristina; Faria, Brígida Mónica; Alves, Sandra Maria; Ferreira, Jorge; Faria, Brigida Monica; Alves, Sandra Maria

Asthma is a respiratory disease characterized by chronic inflammation of the airways. Effective asthma management is essentially based on choosing the appropriate treatment for each individual (1). Data science and machine learning models offer valuable insights and enhance the outcomes achieved in asthma management (2). The main objective is to develop predictive models for therapy response in patients with as...


Report of a rare 3q29 interstitial microdeletion: prenatal diagnosis and postna...

Simão, Laurentino; Pedro, Sónia; Marques, Bárbara; Serafim, Sílvia; Ferreira, Cristina; Tarelho, Ana; Brito, Filomena; Silva, Marisa; Alves, Cristina

Distal interstitial deletions in the 3q29 region are rare. The characterization of new prenatal diagnosis (PND) cases and their follow-up may add knowledge about the affected region.


Musculoskeletal manifestations of acute leukemia

Cordeiro, Catarina; Teixeira, Catarina; Jerónimo, Mónica; Silva, Sónia; Azevedo, Joana; Nascimento, João; Carvalho, Marcos; Tarquini, Oliana

Acute lymphoblastic leukemia (ALL) is the most common cause of malignancy in pediatric age. With the exception of musculoskeletal tumors, ALL is one of the malignancies most commonly associated with musculoskeletal symptoms at initial presentation. Some children with ALL are initially referred to Orthopedics for diagnostic evaluation, and a high index of clinical suspicion is required to avoid diagnostic delay....


Deleção intersticial 7q33q34 em fetos de gravidez gemelar monocoriónica diamnió...

Simão, Laurentino; Marques, Bárbara; Ferreira, Cristina; Serafim, Sílvia; Alves, Cristina; Silva, Marisa; Viegas, Mónica; Peliano, Ricardo

Introdução: O acompanhamento de gestações gemelares pode revelar-se desafiante se houver alterações ecográficas e discrepâncias entre os fetos. Deleções intersticiais 7q, abrangendo diferentes regiões e apresentando tamanho variável, são raras, e encontram-se quase exclusivamente descritas em pós-natal. Objectivos: Apresentamos o caso de uma gestante, de 32 anos, com gravidez gemelar monocoriónica e diamniótica...


The Cost of Meningococcal Meningitis in Portugal

Rodrigues, Fernanda; Pinheiro, Bernardete; Guerreiro, Rita; Gouveia, Miguel; Eloi, João; Alves, Cristina; Castela, Guilherme; Oliveira, Alexandra

Introduction: Invasive meningococcal disease (IMD) is an infection caused by the bacterium Neisseria meningitidis, and a major cause of meningitis (MM) and/or septicemia (MS). The aim of this study is to estimate the costs of IMD (MM and MS) for Portuguese state.Methods: To estimate the costs associated with IMD, a model was developed, where patients can have one of three outcomes: survive without sequelae, sur...


Pregnancy and postpartum depression (PPD): A non-systematic review assessing th...

Alves, Cristina; Soares, Luísa; Faria, Ana Lúcia

Objective: Pregnancy and motherhood, while rewarding, can be challenging and transformative. The gestational and postpartum periods may cause various changes, making women susceptible to mental disorders like Postpartum Depression (PPD). This review aimed to present the current state of knowledge on pregnancy and PPD, with a focus on PPD prevention in pregnant women aged 20-40, as well as PPD prevalence worldwi...


Pregnancy and Postpartum Depression (PPD): a non-systematic review assessing th...

Alves, Cristina; Soares, Luísa; Faria, Ana Lúcia

Objetivo: A gravidez e a maternidade, embora recompensadoras, podem ser desafiadoras e transformadoras. Os períodos gestacional e pós-parto podem causar várias mudanças, tornando as mulheres suscetíveis a transtornos mentais, como a Depressão Pós-Parto (DPP). Esta revisão teve como objetivo apresentar o estado atual do conhecimento sobre a gravidez e a DPP, com foco na prevenção da DPP em mulheres grávidas com ...


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