10 documents found, page 1 of 1
Characterization of Disease Progression in the Initial Stages of Retinopathy in...
Marques, Inês P.; Alves, Dalila; Santos, Torcato; Mendes, Luís; Lobo, Conceição; Santos, Ana Rita; Durbin, Mary; Cunha-Vaz, JoséPURPOSE. To characterize 2-year changes occurring in neurodegeneration, edema, and capillary dropout in nonproliferative diabetic retinopathy. METHODS. Two-year prospective longitudinal observational cohort of eyes/patients with type 2 diabetes using spectral domain optical coherence tomography (SD-OCT) and optical coherence tomography angiography (OCTA). Eyes were examined three times with intervals of 1 year....
Age-Related Macular Degeneration Staging by Color Fundus Photography vs. Multim...
Farinha, Cláudia; Cachulo, Maria da Luz; Coimbra, Rita; Alves, Dalila; Nunes, Sandrina; Pires, Isabel; Marques, João Pedro; Costa, José; Martins, AméliaEpidemiology of age-related macular degeneration (AMD) is based on staging systems relying on color fundus photography (CFP). We aim to compare AMD staging using CFP to multimodal imaging with optical coherence tomography (OCT), infra-red (IR), and fundus autofluorescence (FAF), in a large cohort from the Epidemiologic AMD Coimbra Eye Study. All imaging exams from the participants of this population-based study...
Optical coherence tomography leakage in neovascular age-related macular degener...
Farinha, Cláudia; Santos, Torcato; Santos, Ana Rita; Lopes, Marta; Alves, Dalila; Silva, Rufino; Cunha-Vaz, JoséOptical coherence tomography leakage identified and quantified the fluid related to choroidal neovascularization activity. Low optical reflectivity change in the outer segment layer correlates with functional outcome and increasing LOR in the external layers may be a marker of early recurrence. Combining optical coherence tomography angiography and optical coherence tomography leakage allows both for choroidal ...
Characterization of disease progression in the initial stages of retinopathy in...
Marques, Inês P.; Alves, Dalila; Santos, Torcato; Mendes, Luís; Lobo, Conceição; Santos, Ana Rita; Durbin, Mary; Cunha-Vaz, JoséTo characterize 2-year changes occurring in neurodegeneration, edema, and capillary dropout in nonproliferative diabetic retinopathy. Two-year prospective longitudinal observational cohort of eyes/patients with type 2 diabetes using spectral domain optical coherence tomography (SD-OCT) and opti cal coherence tomography angiography (OCTA). Eyes were examined three times with intervals of 1 year. Thickness of the...
Microperimetry and mfERG as functional measurements in diabetic macular oedema ...
Santos, Ana Rita; Raimundo, Miguel; Alves, Dalila; Lopes, Marta; Pestana, Sérgio; Figueira, João; Cunha-Vaz, José; Silva, RufinoTo evaluate Microperimetry (MP) and multifocal electroretinogram (mfERG) as whole-macula functional markers of treatment response in naive diabetic macular oedema (DMO) patients undergoing ranibizumab treatment. Microperimetry and mfERG were able to demonstrate DMO functional improvement after treatment loading dose, as well as early visual changes when treatment regimen was switched to PRN.
Measurements of retinal fluid by oct leakage in diabetic macular edema: A bioma...
Santos, Ana Rita; Alves, Dalila; Santos, Torcato; Figueira, João; Rufino, Silva; Cunha-Vaz, José G.Optical coherence tomography leakage changes after anti-vascular endothelial growth factor treatment of diabetic macular edema, identifying the degree of decrease in retinal fluid in the outer layers of the retina is a more robust biomarker of BCVA recovery than central retinal thickness, disorganization of the inner retinal layer, or ellipsoid zone disruption changes.
Choroidal Indices as Predictors of Visual Outcomes to anti-VEGF Treatment in DM...
B M Santos, Ana Rita; Alves, Dalila; Lains, Ines; Wang, Jay C; Miller, John B; Figueira, João; Silva, Rufino[Purpose : To evaluate the associations between anti-VEGF therapy and central choroidal thickness (CCT), choroidal vascular density (CVD) and choroidal vascular volume (CVV), in patients with Diabetic Macular Edema (DME) using Swept Source OCT (SS-OCT), and to correlate these findings with treatment visual outcomes.]
Characterization of initial stages of diabetic macular edema
Santos, Ana Rita; Santos, Torcato; Alves, Dalila; Marques, Inês P.; Lobo, Conceição; Cunha-Vaz, JoséThis study is aimed at characterizing the type of retinal edema in the initial stages of retinopathy in type 2 diabetes. In this retrospective cross-sectional study, spectral domain optical coherence tomography (OCT) layer by layer analysis of the retina in association with OCT-Leakage, an algorithm to detect sites of low optical reflectivity, were used to examine eyes with minimal, mild, and moderate diabetic ...
Adherence to a Mediterranean diet, lifestyle and age-related macular degenerati...
Raimundo, Miguel; Mira, Filipe; Cachulo, Maria da Luz; Barreto, Patrícia; Ribeiro, Luísa; Farinha, Cláudia; Laíns, Inês; Nunes, Sandrina; Alves, DalilaPurpose To characterize the lifestyle and nutritional risk profile associated with the Mediterranean diet in a Portuguese population with and without age‐related macular degeneration (AMD). Methods Nested case–control study (n = 883) within the Coimbra Eye Study, including 434 subjects with AMD and 449 age‐ and sex‐matched subjects without AMD. All enrolled subjects underwent a full risk assessment, including l...
Optical coherence tomography baseline predictors for initial best-corrected vis...
B M Santos, Ana Rita; Costa, Miguel Â; Schwartz, Christian; Alves, Dalila; Figueira, João; Silva, Rufino; Cunha-Vaz, Jose GPurpose: To identify baseline optical coherence tomography morphologic characteristics predicting the visual response to anti-vascular endothelial growth factor therapy in diabetic macular edema. Methods: Sixty-seven patients with diabetic macular edema completed a prospective, observational study (NCT01947881-CHARTRES). All patients received monthly intravitreal injections of Lucentis for 3 months followed by ...