3 documents found, page 1 of 1
Evaluation of Raw Cheese as a Novel Source of Biofertilizer with a High Level o...
Nunes, Ana R.; Sánchez-Juanes, Fernando; Gonçalves, Ana C.; Alves, Gilberto Lourenço; Silva, Luís R.; Flores-Félix, José DavidToday’s agriculture requires the search for new and modern tools in order to improve and expand the use of its crops and to increase their sustainability. The use of plant growth-promoting PGP bacteria (PGPB) is the target of much research and seems to be an ideal strategy as long as the strains are properly selected for this purpose. Among the bacteria, lactic acid bacteria (LAB) are considered a suitable alte...
Strategies to Improve Drug Strength in Nasal Preparations for Brain Delivery of...
Pires, Patrícia C.; Rodrigues, Márcio; Alves, Gilberto Lourenço; Santos, Adriana O.Intranasal administration is a promising route for brain drug delivery. However, it can be difficult to formulate drugs that have low water solubility into high strength intranasal solutions. Hence, the purpose of this work was to review the strategies that have been used to increase drug strength in intranasal liquid formulations. Three main groups of strategies are: the use of solubilizers (change in pH, comp...
Caracterização farmacocinética do acetato de eslicarbazepina e dos seus metabol...
Alves, Gilberto LourençoTese de doutoramento em Farmácia (Farmacologia) apresentada à Fac. de Farmácia da Universidade de Coimbra; O acetato de eslicarbazepina (ESL), designado inicialmente como BIA 2-093, é um novo fármaco que exerce os seus efeitos pelo bloqueio dos canais de sódio dependentes da voltagem, em desenvolvimento clínico para o tratamento da epilepsia, da perturbação bipolar e da dor neuropática. O ESL é um composto quím...