31 documents found, page 1 of 4
Profiling of urinary extracellular vesicle protein signatures from patients wit...
Bernardino, R; Carvalho, AS; Hall, MJ; Alves, L; Leão, R; Sayyid, R; Pereira, H; Beck, HC; Campos-Pinheiro, L; Henrique, R; Fleshner, N; Matthiesen, RPrognostic tests and treatment approaches for optimized clinical care of prostatic neoplasms are an unmet need. Prostate cancer (PCa) and derived extracellular vesicles (EVs) proteome changes occur during initiation and progression of the disease. PCa tissue proteome has been previously characterized, but screening of tissue samples constitutes an invasive procedure. Consequently, we focused this study on liqui...
Contacts with health services for COVID-19-related reasons during the first wav...
Granja, M; Correia, D; Alves, L; Severo, M; Lucas, R; Correia, S; ISPUP/INESC TEC Task Force COVID-19"Introduction: Access to COVID-19-related care during the pandemic deserve attention and study to inform future strategies to deal with similar health emergencies in the future. We aimed to describe access to care for COVID-19-related reasons during the first 9 weeks of the pandemic in Portugal, to quantify the frequency of remote and in-person contacts with healthcare for COVID-19-related reasons and to assess...
First contact with the health system: a survey study in northern Portugal
Granja, M; Alves, L; Correia, SObjective The objective of this study is to characterise the self-reported first contact with the health system and the reasons stated for each choice, testing associations with population characteristics. Design Cross-sectional survey. Setting Primary care department of a local health unit in northern Portugal. Participants Random sample of 4286 persons, retrieved from all registered adults. Outcomes Participa...
Access to General Practitioners during the COVID-19 pandemic in Portugal-A surv...
Granja, M; Alves, L; Correia, SBackgroundIn 2020, Portugal had high levels of unmet health care needs. Primary Care was reported as the main source of unmet needs. ObjectivesTo describe face-to-face and remote access to GPs in Portugal during the COVID-19 pandemic. To discover patient experiences and attitudes to access to care. To identify determinants of access to care. MethodsA survey of a random sample of 4,286 adults registered in a gro...
Access to General Practitioners during the second year of the COVID-19 pandemic...
Granja, M; Correia, S; Alves, LBackgroundThe Portuguese National Health System (NHS) provides universal coverage and near-free health care, but the population has high out-of-pocket expenses and unmet care needs. This suggests impaired accessibility, a key dimension of primary care. The COVID-19 pandemic has further affected access to health care. Understanding General Practitioners' (GP) experiences during the pandemic is necessary to recon...
[The Impact of the COVID-19 Pandemic on the Healthcare System and on the Mental...
Outeirinho, C; Braga, R; Costa Gomes, J; Alves, L; Cruz, AMIntroduction: The COVID-19 pandemic forced the reorganization of primary health care services. The aim of this study was to describe how the health services responded to organizational requests; how the health services involved and supported their employees; how professionals perceived their involvement in the procedures and what support was provided to them. Additions aims included assessing the levels of anxi...
Scrofula Caused by Multidrug-Resistant Tuberculosis
Pedro, B; Alves, L; Magano, R; Nunes, T; Marques, NTuberculosis (TB) is one of the top 10 causes of death worldwide. Multidrug-resistant tuberculosis (MDR-TB) occurs when at the minimum there is resistance to isoniazid and rifampin. Prevention of new infections of Mycobacterium tuberculosis and progression to TB disease is critical to reduce the burden and mortality of this disease. We present the case of a 73-year-old human immunodeficiency virus (HIV)-negativ...
Healthcare services and medication use among cancer survivors and their partner...
Costa, AR; Alves, L; Lunet, NPurpose. To estimate the association between a cancer diagnosis and the use of healthcare services and medication among cancer survivors (CS) and their partners (PCS), particularly in the first years after diagnosis. Methods. This is a cross-sectional study based on data from the Fourth Wave of the Survey of Health, Ageing and Retirement in Europe—SHARE (2010–2011); it included individuals aged ≥ 50 years and t...
Healthcare services and medication use among widowed partners of patients decea...
Costa, AR; Alves, L; Lunet, NObjective This study aimed to quantify the effect of a cancer death on healthcare and medication use among widowed individuals (Widowed-Cancer), by comparing this population with partnered individuals and with widowed individuals whose partners were deceased due to cardiovascular diseases (Widowed-CVD). Methods Data were retrieved from the Sixth Wave of the Survey of Health, Ageing and Retirement in Europe - SH...
Hepatitis E Virus Genotype 1 Cases Imported to Portugal from India, 2016
Mesquita, JR; Almeida-Santos, M; Fernandes, M; Maltez, F; Lino, S; Alves, L; Abreu-Silva, J; Oliveira, R; Curran, M; Nascimento, MHepatitis E in industrialized countries is mainly associated with genotype 3 hepatitis E virus (HEV) and normally causes a sporadic self-limiting disease in immunocompetent individuals. Unlike genotype 3, genotypes 1 and 2 circulate in developing countries, produce severe disease and occur in the epidemic form. Hepatitis E occurring in travellers returning from endemic areas in developing countries is not a nov...