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Alterations in mucosa branched N-glycans lead to dysbiosis and downregulation o...
Rodrigues, CS; Gaifem, J; Pereira, MS; Alves, MF; Silva, M; Padrão, N; Cavadas, B; Moreira-Barbosa, C; Alves, I; Marcos-Pinto, R; Torres, J; Lavelle, AThe perturbation of the symbiotic relationship between microbes and intestinal immune system contributes to gut inflammation and Inflammatory Bowel Disease (IBD) development. The host mucosa glycans (glycocalyx) creates a major biological interface between gut microorganisms and host immunity that remains ill-defined. Glycans are essential players in IBD immunopathogenesis, even years before disease onset. Howe...
Date: 2025
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Origin: Repositório Aberto da Universidade do Porto