280 documents found, page 1 of 28

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Optimization and Validation of the SBSE–HPLC–FLD Method for the Determination o...

Fernandes-Lage, Eduardo; Alves, Maria José; Moura, Cosme; Garcia, Juliana

Polycyclic aromatic hydrocarbons (PAHs) are priority pollutants in drinking and environmental waters. Their mutagenic/carcinogenic potential and ng.L-1 limits demand methods that are both sensitive and practical. We report a rapid, solvent-sparing workflow coupling stir-bar sorptive extraction (SBSE) to HPLC with fluorescence detection (FLD) for simultaneous determination of six PAHs (fluoranthene, benzo[b]fluo...

Date: 2026   |   Origin: Biblioteca Digital do IPB

Unveiling the impact of thermal water in German chamomile infusions: effects on...

Silveira, Tayse F. F. da; Echegaray, Noemí; Guimarães, Rafaela; Lemos, André; Pires, Tânia C.S.P.; Ferreira, Isabel C.F.R.; Alves, Maria José

German chamomile (GC) and thermal water (TW) are widely known for their biological properties. This study explored whether combining GC with TW could promote an improvement in the bioactivities of GC infusions compared to using drinking water (DW). DW was tested at 100 ◦C (GC-100DW) and TW at both 100 ◦C (GC-100TW) and 60 ◦C (GC-60TW). The use of TW for preparing infusions was associated with the reduction of t...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Natural Mineral Water–Plant Extract Combinations as Potential Anti-Aging Ingred...

Gomes, Carolina P.; Oliveira, Ana S.; Rolo, Joana; Silveira, Tayse F. F. da; Palmeira de Oliveira, Rita; Alves, Maria José; Plasencia, Paula

Natural mineral waters (NMWs) and plant extracts have long been valued for their therapeutic properties and skin benefits. This study investigated, in vitro, the role of five Portuguese NMWs (A-E), combined with plant extracts from five species (Ficus carica L., Rubus idaeus L., Vaccinium myrtillus, Cistus ladanifer and Thymus x citriodorus) as bioactive ingredients. Antioxidant capacity was assessed using the ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Plant-Derived Bioactive Compounds: One Health Perspective

Gonçalves, Ana Carolina Almeida; Pinto, Ana R.; Cima, André; Olo-Fontinha, Eva; Martins, Joana; Garcia, Juliana; Lemos, André; Saavedra, Maria José

This review, within the One Health framework, compiles information on plant-derived bioactive compounds and emphasises their multifunctional role in improving environmental, animal, and human health. These compounds support sustainable health and ecological stability by influencing biological and environmental processes. Data from literature research are combined to explain the mechanisms and potential uses of ...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Assessing the nutritional and functional properties of mushrooms from North-Eas...

Martins, Joana; Garcia, Juliana; Gouvinhas, Irene; Pinto, Diana; Rodrigues, Francisca; Saavedra, Maria José; Alves, Maria José

Mushrooms are recognized as functional foods with noteworthy nutritional, culinary, and pharmacological properties, leading to their growing consumption. The present study aimed to compare the chemical composition and biological properties of six wild species harvested in north-eastern Portugal and two cultivated species (Lentinula edodes and Pleurotus citrinopileatus, purchased in Portuguese retail markets) to...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Exploring the Impact of Ultrasound-Assisted Extraction on the Phytochemical Com...

Gouvinhas, Irene; Saavedra, Maria José; Alves, Maria José; Garcia, Juliana

The health benefits of Tamus communis fruits have been associated with their high phenolic content, which comprises several flavonoids. However, the extraction methods might significantly impact these valuable compounds' bioactivity. Therefore, the current study assesses how different extraction techniques affect T. communis extracts' antioxidant, anti-aging, antimicrobial, cytotoxic, anti-inflammatory, and phe...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Unlocking Nature’s Anti-Aging Secrets: The Potential of Natural Mineral Waters ...

Gama, Ana Rita; Gomes, Carolina P.; Caetano, Cátia; Oliveira, Ana Sofia; Rolo, Joana; Barros, Lillian; Plasencia, Paula; Garcia, Juliana

Skin aging is influenced by intrinsic and extrinsic factors, leading to structural changes in the skin. Current anti-aging cosmetic trends emphasize innovative natural ingredients, including plant extracts, thermal waters, and botanical hydrolats. This work aims to develop six natural anti-aging cosmetics (two serums, two day creams, and two night creams) with innovative and non-irritating profiles. The rationa...

Date: 2025   |   Origin: Biblioteca Digital do IPB

Impact of wildfire emissions exposure on the associations between levels of lun...

Barros, Bela; Paiva, Ana Margarida; Azevedo, Rui; Alves, Sara; Esteves, Filipa; Fernandes, Adília; Vaz, Josiana; Alves, Maria José; Slezakova, Klara

Firefighters face increased risks of developing cardio-respiratory diseases and cancer. This study aimed, for the first time, to simultaneously characterize several biomarkers of effect (lung injury by Clara cell 16 -CC16, lipid peroxidation by 8-isoprostane-8-iso, and DNA oxidation by 8-hydroxy-2-deoxyguanosine-8-OHdG) and exposure (polycyclic aromatic hydrocarbons metabolites - 6 OHPAHs and 17 metal(loid)s) i...


Plant-derived bioactive compounds: one health perspective

Gonçalves, Ana C.; Pinto, Ana R.; Cima, André; Olo-Fontinha, Eva; Martins, Joana C. L.; Garcia, Juliana; Lemos, André; Saavedra, Maria José

This review, within the One Health framework, compiles information on plant-derived bioactive compounds and emphasises their multifunctional role in improving environmental, animal, and human health. These compounds support sustainable health and ecological stability by influencing biological and environmental processes. Data from literature research are combined to explain the mechanisms and potential uses of ...


Usage of thermal spring water for optimal skin health: bridging traditional the...

Rocha, Pedro Emanuel; Alves, Maria José; Fidalgo, Cátia; Correia, Daniela; Pedrosa, Silvia; Madureira, Ana Raquel

Thermal spring waters (TSW) have been employed forntherapeutic purposes across the centuries being increasingly recognized for its unique benefits in skin health, in which immunomodulatory effects play a crucial role. By reviewing the literature, the multifaceted properties of TSW, which arise from its diverse mineral composition as well as its thermal characteristics, revealed the strong potential of these wat...

Date: 2025   |   Origin: Biblioteca Digital do IPB

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