42 documents found, page 1 of 5
Impact of cannabidiol and delta-9-tetrahydrocannabinol in the angiogenic role o...
Alves, P.; Amaral, C.; Teixeira, N.; Correia-da-Silva, G.Background: Cannabis is the most consumed illicit drug in Europe. Alongside, the medicinal use of cannabinoids is rising. Indeed, a formulation that combines the major phytocannabinoids, cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) in a 1:1 proportion (Sativex®), is already available for the management of multiple sclerosis. Nevertheless, a lot remains unknown in relation to cannabinoid’s impact in ...
A view on polymer-based composite materials for smart wound dressings
Baptista-Silva, S.; Alves, P.; Guimarães, I.; Borges, S.; Tavaria, F.; Granja, P.; Pintado, M.; Oliveira, A. L.Wound management challenges everyday thousands of health professionals, mainly due to the constant monitoring and difficulties in deciding the correct treatment options. When considering chronic wounds, selecting the ideal dressing defies clinical knowledge, when facing the large amount of different materials, its distinctive properties and the uniqueness of each patient needs. This chapter presents an overview...
The Portuguese National Seismic Network —Products and Services
Carrilho, F.; Custodio, S.; Bezzeghoud, M.; Oliveira, C. S.; Marreiros, C.; Vales, D.; Alves, P.; Pena, A.; Madureira, G.; Escuer, M.; Silveira, G.Portugal, located in the southwest region of the Eurasian plate, has been affected by several destructive earthquakes throughout its history, the most well-known being the 1755 Great Lisbon earthquake. The seismicity of the territory, both in the mainland and in the Azores and Madeira islands, has prompted the continuous development of seis- mic monitoring, from the first known macroseismic inquiry, following t...
Crowdsourcing-based fingerprinting for indoor location in multi-storey buildings
Santos, R.; Leonardo, R.; Barandas, M.; Moreira, D.; Rocha, T.; Alves, P.; Oliveira, J.; Gamboa, H.The number of available indoor location solutions has been growing, however with insufficient precision, high implementation costs or scalability limitations. As fingerprinting-based methods rely on ubiquitous information in buildings, the need for additional infrastructure is discarded. Still, the timeconsuming manual process to acquire fingerprints limits their applicability in most scenarios. This paper prop...
Polyester-based photocrosslinkable bioadhesives for wound closure and tissue re...
Santos, M.; Cernadas, T.; Martins, P.; P. Miguel, Sónia; Correia, I.J.; Alves, P.; Ferreira, P.Photocrosslinkable surgical adhesives provide many advantages when compared with traditional methods used in wound closure. This work aimed to develop UV-curable biodegradable adhesives based on lactic acid and PCL oligomers. Both materials were functionalized with 2-isocyanatoethyl acrylate (AOI). Subsequently, the photoinitiator (Irgacure® 2959) was added to the blend and then, the final materials were irradi...
Strategic talent management: the impact of employer branding on the affective c...
Alves, P.; Santos, V.; Reis, I. P. Dos; Martinho, F.; Martinho, D.; Sampaio, M. C.; Sousa, M.; Au-Yong-Oliveira, M.In a globalization context, underlined by the speed of technological transformation and increasingly competitive markets, the perspective of human capital, as an asset of strategic importance, stands out in differentiating human resource practices. Under this reality, the employer branding (EB) concept gains more and more importance as a strategic tool to attract, retain, and involve human capital, given that t...
Real-world data from the Portuguese Nivolumab Expanded Access Program (EAP) in ...
Figueiredo, A.; Almeida, M.A.; Almodovar, M.T.; Alves, P.; A, Araujo; Araújo, D.; Barata, F.; Barradas, L.; Barroso, A.; Brito, U.; Camacho, E.Objective: The main aim of the study was to evaluate the efficacy and safety profile of Nivolumab, an immune-checkpoint-inhibitor antibody, in advanced, previously treated, Non-Small Cell Lung Cancer (NSCLC) patients, in a real world setting. Methods: We performed a retrospective, multicentre data analysis of patients who were included in the Portuguese Nivolumab Expanded Access Program (EAP). Eligibility crite...
Manual de intervenção alimentar e nutricional na COVID-19
Gregório, Maria João; Irving, S.; Sousa, S.M.; Ferreira, B.; Figueira, I.; Ferro, G.; Alves, P.; Graça, Pedro
Breve história das introduções biológicas em Portugal Continental. In: As invas...
Ribeiro, F.; Aguiar, C.; Anastácio, P.M.; Capinha, C.; Grosso-Silva, J.M.; Matias, R.; Polónia, A.; Segurado, P.; Sousa, R.; Alves, P.Desde o início da civilização existiram movimentações de plantas e animais, por ação humana. Neste capítulo, são analisados cronologicamente os primeiros registos das introduções de espécies não indígenas em Portugal continental e suas regiões de origem. Ao longo do tempo, o número de espécies não indígenas de plantas foi sempre superior ao número de animais. O aumento no número de registos de plantas introduzi...
Biofilm formation behaviour of marine filamentous cyanobacterial strains in con...
Romeu, M.J.; Alves, P.; Morais, J.; Miranda, J.M.; de Jong, E.; Sjollema, J.; Ramos, V.; Vasconcelos, V.; Mergulhão, F.J.M.Marine biofouling has severe economic impacts and cyanobacteria play a significant role as early surface colonizers. Despite this fact, cyanobacterial biofilm formation studies in controlled hydrodynamic conditions are scarce. In this work, computational fluid dynamics was used to determine the shear rate field on coupons that were placed inside the wells of agitated 12-well microtiter plates. Biofilm formation...