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Distinct exercise modalities on GUT microbiome in sarcopenic older adults: stud...
Merelim, Ana Sofia; Zacca, Rodrigo; Moreira-Gonçalves, Daniel; Costa, Paulo P.; C. Baptista, LilianaBackground: Sarcopenia is a progressive and age-related skeletal muscle disease related to adverse health outcomes and to an increased economic burden. Recent evidence pinpoints the human gut microbiota (GM) as a contributing factor in the development of sarcopenia via the gut-muscle axis. To date, no study specifically analyzed the optimal type of exercise modality in older adults with sarcopenia considering t...
Lifelong exercise training promotes the remodelling of the immune system and pr...
Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Palmeira, Carlos; Martins, Gabriela; Fonseca, Carolina; Duarte, José Alberto; Faustino-Rocha, Ana IThis work aimed to understand how lifelong exercise training promotes the remodelling of the immune system and prostate signalome in a rat model of PCa. Fifty-five male Wistar rats were divided into four groups: control sedentary, control exercised, induced PCa sedentary and induced PCa exercised. Exercised animals were trained in a treadmill for 53 weeks. Pca induction consisted on the sequential administratio...
Exercise training impacts skeletal muscle remodelling induced by metabolic synd...
Nogueira-Ferreira, Rita; Santos, Inês; Ferreira, Rita; Fontoura, Dulce; Sousa-Mendes, Cláudia; Falcão-Pires, Inês; Lourenço, André P.Metabolic syndrome (MetS), characterized by a set of conditions that include obesity, hypertension, and dyslipidemia, is associated with increased cardiovascular risk. Exercise training (EX) has been reported to improve MetS management, although the underlying metabolic adaptations that drive its benefits remain poorly understood. This work aims to characterize the molecular changes induced by EX in skeletal mu...
Patiente -reported experience in colorectal cancer continuum of care. How to tr...
Carvalho Pinto, Cristina; Pereira, Filipe Miguel Soares; Santos, Cristina Mendes; Teixeira, Fátima; Moreira-Gonçalves, Daniel; Santos, Lúcio LaraBackground: Patient-focused interventions recognize the role of patients as active participants in the process of delivering effective, safe and responsible healthcare. When equipped with appropriate knowledge, patients can play an important role in their own care by early diagnosing self-limiting conditions and establishing a beneficial relationship with the healthcare team. The purpose of this study was to id...
Effects of physical exercise in biochemical parameters and dorsolateral prostat...
Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Faustino-Rocha, Ana Isabel; Pires, Maria João; Neuparth, Maria João; Moreira-Gonçalves, DanielBackground: Prostate cancer (PCa) is among the most prevalent cancers worldwide. Physical exercise is widely recognized due to its beneficial effects. This study aimed to evaluate the effects of physical exercise on biochemical pa- rameters and in dorsolateral prostate lesions in a rat model of PCa. Materials and Methods: Ninety-five male Wistar Unilever rats were randomly divided into eight groups sacrificed a...
Effects of physical exercise in biochemical parameters and dorsolateral prostat...
Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Faustino-Rocha, Ana Isabel; Pires, Maria João; Neuparth, Maria João; Moreira-Gonçalves, DanielProstate cancer (PCa) is among the most prevalent cancers worldwide. Physical exercise is widely recognized due to its beneficial effects. This study aimed to evaluate the effects of physical exercise on biochemical parameters and in dorsolateral prostate lesions in a rat model of PCa. Ninety-five male Wistar Unilever rats were randomly divided into eight groups sacrificed at 35 (groups I) or 61 weeks of age (g...
Exercise training as a potential therapeutic agent for prostate neoplasia in a ...
Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Lemos, Sílvia; Faustino-Rocha, Ana Isabel; Pires, Maria João; Neuparth, Maria JoãoIntroduction: Exercise training is widely recognized for its beneficial health outcomes, namely in prostate cancer (PCa). This study aimed to evaluate the effect of exercise training on dorsolateral prostate lobe lesions in a rat model of chemically and hormonally induced prostate cancer. Material & methods: Fifty-five male Wistar Unilever rats (Rattus norvegicus) of 12 weeks of age were randomly divided into f...
Effect of exercise training on lymphocyte subpopulations in chemically and horm...
Nascimento-Gonçalves, Elisabete; Faustino-Rocha, Ana Isabel; Palmeira, Carlos; Duarte, José Alberto; Moreira-Gonçalves, Daniel; Colaço, BrunoIntroduction: Long-term and regular exercise training is suggested to have an immunomodulatory effect, protecting against several diseases. This work aimed to analyse the effect of exercise training on peripheral lymphocyte subpopulations in a model of prostate cancer (PCa) chemically and hormonally induced. Methods: Fifty-five male Wistar Unilever rats of 4 weeks of age were randomly divided into four experime...
Effect of exercise training on lymphocyte subpopulations in chemically and horm...
Nascimento-Gonçalves, Elisabete; Faustino-Rocha, Ana Isabel; Palmeira, Carlos; Duarte, José Alberto; Moreira-Gonçalves, Daniel; Colaço, BrunoIntroduction: Long-term and regular exercise training is suggested to have an immunomodulatory effect, protecting against several diseases. This work aimed to analyse the effect of exercise training on peripheral lymphocyte subpopulations in a model of prostate cancer (PCa) chemically and hormonally induced. Methods: Fifty-five male Wistar Unilever rats of 4 weeks of age were randomly divided into four experime...
Physical exercise in a chemically and hormonally induced rat model of prostate ...
Nascimento-Gonçalves, Elisabete; Seixas, Fernanda; Faustino-Rocha, Ana Isabel; Pires, Maria João; Neuparth, Maria João; Moreira-Gonçalves, DanielIntroduction: Physical exercise is widely recognized for its beneficial health effects, namely in prostate cancer (PCa). This study aimed to evaluate the effect of physical exercise in a rat model of chemically and hormonally induced PCa.Results: Body weight was lower in exercised groups than in sedentary, either in control or in PCa groups (p<0.05) (Fig. 2). PCa and exercise training increased the prostate rel...