5 documents found, page 1 of 1
Influence of TLR-2 in the immune response in the infection induced by fungus Sp...
Negrini, Thais De C. [UNESP]; Ferreira, Lucas S. [UNESP]; Arthur, Rodrigo A.; Alegranci, Pâmela [UNESP]; Placeres, Marisa C. P. [UNESP]Made available in DSpace on 2022-04-29T07:14:31Z (GMT). No. of bitstreams: 0 Previous issue date: 2014-01-01; Toll-like receptors (TLRs) play an important role in immunity, since they bind to pathogen surface antigens and initiate the immune response. However, little is known about the role of TLR-2 in the recognition of S. schenckii and in the subsequent immune response. Therefore, the aim of this study was to...
Chemopreventive activity of systemically administered curcumin on oral cancer i...
De Paiva Gonçalves, Vinícius [UNESP]; Ortega, Adriana Alicia C. [UNESP]; Guimarães, Morgana R. [UNESP]; Curylofo, Fabiana Almeida [UNESP]Made available in DSpace on 2022-04-29T07:25:54Z (GMT). No. of bitstreams: 0 Previous issue date: 2015-01-01; Curcumin has therapeutic potential in preventing several types of cancer, including colon, liver, prostate, and breast. The goal of this study was to evaluate the chemopreventive activity of systemically administered curcumin on oral carcinogenesis induced by 4-nitroquinolone-1-oxide (4-NQO). A total of...
Physiological effects of tangeretin and heptamethoxyflavone on obese C57BL/6J m...
Nery, Marina [UNESP]; Ferreira, Paula S. [UNESP]; Gonçalves, Danielle R. [UNESP]; Spolidorio, Luis C. [UNESP]; Manthey, John A.; Cesar, Thais B. [UNESP]Made available in DSpace on 2021-06-25T10:52:35Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-04-01; Two compounds from citrus peel, tangeretin (TAN) and 3′,4′,3,5,6,7,8-heptamethoxyflavone (HMF), were investigated for their abilities to repair metabolic damages caused by an high-fat diet (HFD) in C57BL/6J mice. In the first 4 weeks, mice were fed either a standard diet (11% kcal from fat) for the cont...
Resistin Is Increased in Periodontal Cells and Tissues: In Vitro and in Vivo St...
Nogueira, Andressa V. B.; Nokhbehsaim, Marjan; Tekin, Sema; De Molon, Rafael S. [UNESP]; Spolidorio, Luis C. [UNESP]; Memmert, Svenja; Damanaki, AnnaMade available in DSpace on 2020-12-12T01:56:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Resistin, a proinflammatory adipokine, is elevated in many inflammatory diseases. However, little is known about its performance in periodontitis. The present study is aimed at evaluating resistin expression and synthesis in periodontal cell...
Role of NOD2 and RIP2 in host-microbe interactions with Gram-negative bacteria:...
Souza, Joao A.C. [UNESP]; Medeiros, Marcell C. [UNESP]; Rocha, Fernanda R.G. [UNESP]; De Aquino, Sabrina G. [UNESP]; Ávila-Campos, Mario J.Made available in DSpace on 2018-12-11T17:07:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-11-01; National Institute of Dental and Craniofacial Research; NOD2 is a member of the NLR family of proteins that participate in the activation of the innate immune response. RIP2 is a downstream kinase activated by both NOD1 and NOD2. There is scarcity of information regarding the relevance of NOD2 in period...