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Calciphylaxis in Pre-dialysis Chronic Kidney Disease: Case Report
Ferreira,André; Calado,Rebeca; Cardoso,José Carlos; Galvão,Ana; Alves,RuiAbstract Calciphylaxis is a rare life‑threatening vasculopathy resulting from calcium deposition in the arteriolar microvasculature of the deep dermis and subcutaneous adipose tissue, mainly occurring in end‑stage kidney disease (ESKD) treated with maintenance dialysis. Calciphylaxis in patients without ESKD is even rarer, which makes the diagnosis of calciphylaxis challenging in this population. In patients wi...
Successful management of a fetal mediastinal teratoma − Case report
Carvalho,Carolina Castro de; Ferreira,Leonor; Caetano,Paula; Carneiro,Rita Cabrita; Alves,Rui; Bernardo,Ana; Cohen,ÁlvaroAbstract Fetal mediastinal teratomas are rare tumors that can cause prenatal hydrops and respiratory distress during the neonatal period. Given their rarity and potential for serious complications, these cases require management by a multidisciplinary team of experts, ideally within a specialized referral center. The authors describe the case of a primigravida with a fetal mediastinal teratoma who was managed e...
Does Prior Abdominal Surgery Influence Technique Survival of Peritoneal Dialysi...
Silva,Rita Matos; Fragoso,Pedro; Reis,Marina; Cerqueira,Sofia; Romãozinho,Catarina; Borges,Andreia; Maia,Pedro; Ferreira,Joaquim; Mendes,TeresaAbstract Introduction: Prior abdominal surgery may result in peritoneal membrane adhesions and fibrosis. Its impact on peritoneal membrane function and peritoneal dialysis technique survival has not been adequately investigated. The aim of our study was to investigate the effect of prior abdominal surgical procedures on peritoneal dialysis technique survival. Methods: We performed a retrospective, longitudinal ...
The Importance of a Peritoneal Dialysis‑First Policy in Long Term Outcomes
Correia,Ana Luísa; Almiro e Castro,Pedro; Mira,Filipe; Cerqueira,Sofia; Marques,Maria Guedes; Maia,Pedro; Alves,RuiAbstract Introduction: A significant part of peritoneal dialysis (PD) patients begins renal replacement therapy (RRT) through hemodialysis (HD) before transitioning to PD. We aim to evaluate the impact of an initial period on HD before transitioning to PD on the outcomes. Material and Methods: We conducted a retrospective cohort study including the prevalent PD patients between January 2017 and December 2019. D...
Clinical Presentation and Treatment of Childhood-Onset Lupus Nephritis
Silva,Rita M.; Correia,Ana L.; Marques,Maria G.; Cordinhã,Carolina; Romãozinho,Catarina; Oliveira,Nuno A.; Carmo,Carmen do; Gomes,Clara; Alves,RuiAbstract Introduction: Lupus nephritis (LN) in childhood usually presents after the age of 10 years and is more common in female children. Despite the availability of effective immunosuppressive therapies, treatment response in childhood‑onset LN remains suboptimal, with 50% to 78% patients in full remission at 24 months. Improvement in survivals have also plateaued in past decades, and up to 9% and 14% of chil...
Endoscopic Retrograde Cholangiopancreatography on Pediatric Patients: Experienc...
Saraiva,Rita Ornelas; Borges,Verónica Pavão; Silva,Mário Jorge; Loureiro,Rafaela; Capela,Tiago; Ramos,Gonçalo; Canena,Jorge; Dias,António MateusAbstract Introduction: Experience with endoscopic retrograde cholangiopancreatography (ERCP) in the pediatric population is limited. Few medical centers have experts specifically trained in pediatric therapeutic endoscopy. As a result, patients are generally referred to adult endoscopists with high experience in the procedure. The aim of this study was to characterize the experience of an adult endoscopy unit w...
Life and Sleep Quality amongst Peritoneal Dialysis Patients: A Comparative Study
Castro,Pedro Almiro e; Correia,Ana Luísa; Mira,Filipe; Cerqueira,Sofia; Oliveira,Nuno Afonso; Maia,Pedro; Alves,RuiABSTRACT Introduction: Sleep disorders affect up to 70% of peritoneal dialysis (PD) patients and appear to have significant negative effects on their quality of life (QoL). We compared life and sleep quality between patients on automated PD (APD) and continuous ambulatory PD (CAPD). Material and Methods: Cross-sectional study in chronic PD patients followed in our Dialysis Unit in February 2022. We evaluated sl...
Systemic Lupus Concealed in the Shadow of a Primary Membranous Nephropathy Diag...
Castro,Pedro Almiro e; Mira,Filipe; Oliveira,Nuno Afonso; Alves,RuiABSTRACT A 43-year-old male patient followed for 27 years in a Nephrology consultation with negative autoimmune diagnostic workup and a histologically proven membranous nephropathy (MN), interpreted as a primary MN. During the follow-up he had multiple relapses, requiring continuous immunosuppression. Eventually, end-stage renal disease developed and the patient started hemodialysis (HD) in January 2018. Soon a...
Early Antibody-Mediated Kidney Transplant Rejection: A Successful Case Without ...
Silva,Rita M.; Leal,Rita; Marques,Maria G.; Rodrigues,Luís; Santos,Lídia; Romãozinho,Catarina; Figueiredo,Arnaldo; Alves,RuiABSTRACT The diagnosis of antibody-mediated rejection has become more common and represents a major cause of kidney graft loss. The ideal treatment remains unknown, with little evidence supporting the use of a specific therapy. The definition of antibody-mediated rejection is based on serologic (presence and/or development of donor-specific antibodies) and histologic (evidence of acute tissue injury with C4d de...
Comparing Kidney Care during the Pandemic in Hospitalized Non-COVID-19 Patients
Silva,Rita M.; Mira,Filipe; Costa,Regina; Reigota,Catarina; Romãozinho,Catarina; Santos,Lèlita; Alves,RuiAbstract Introduction: Coronavirus disease 19 (COVID-19) has caused a direct increase in mortality but not all of it is entirely attributable to COVID-19, meaning there was a higher rate of mortality in non-COVID-19 patients due to the pandemic. The aim of this study was to compare two groups of patients: group 1, which included all of the patients admitted to the Internal Medicine ward during the month of Apri...