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Development of multicore hybrid particles for drug delivery through the precipi...

Gonçalves, V. S. S.; Rodríguez-Rojo, S.; Matias, A. A.; Nunes, A. V. M.; Nogueira, I. D.; Nunes, D.; Fortunato, E.; Alves de Matos, A. P.; Cocero, M. J.

Hybrid lipid–polymer particles are gaining increasing interest to be applied as drug delivery systems due to their greater stability in biological fluids and enhanced cellular uptake of drugs. However, a major drawback is the fact that these particles are usually produced through techniques that use organic solvents. This work studies the possibility of producing for the first time hybrid particles composed by ...


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