4 documents found, page 1 of 1
Allogenic synovia-derived mesenchymal stem cells for treatment of equine tendin...
Reis, Inês Leal; Lopes, Bruna; Sousa, Patrícia; Sousa, Ana Catarina; Branquinho, Mariana; Caseiro, Ana Rita; Pedrosa, Sílvia Santos; Rêma, AlexandraTendon and ligament injuries are frequent in sport horses and humans, and such injuries represent a significant therapeutic challenge. Tissue regeneration and function recovery are the paramount goals of tendon and ligament lesion management. Nowadays, several regenerative treatments are being developed, based on the use of stem cell and stem cell-based therapies. In the present study, the preparation of equine...
Dextrin hydrogel loaded with a macroporous Bonelike® scaffold and dental pulp s...
Machado, A.; Pereira, Isabel; Pereira, José Eduardo; Maltez, Luís; Brandão, Ana; Alvites, Rui; Sousa, Ana Catarina; Branquinho, MarianaRegeneration of severe bone defects remains a challenge. A formulation of synthetic glass-reinforced hydroxyapatite bone substitute, Bonelike® Poro (BL®P), 250500 µm-diameter, with a dextrin-based hydrogel (HG), further loaded with human dental pulp stem cells (hDPSCs) with osteogenic differentiation ability, was tested for the management of critical-sized defects in an ovine model. Morphology, calcium release,...
Dextrin hydrogel loaded with a macroporous Bonelike® scaffold and dental pulp s...
Machado, Alexandra; Pereira, Isabel; Pereira, José Eduardo; Maltez, Luís; Brandão, Ana; Alvites, Rui; Sousa, Ana Catarina; Branquinho, MarianaRegeneration of severe bone defects remains a challenge. A formulation of synthetic glass-reinforced hydroxyapatite bone substitute, Bonelike® Poro (BL®P), 250–500 µm-diameter, with a dextrin-based hydrogel (HG), further loaded with human dental pulp stem cells (hDPSCs) with osteogenic differentiation ability, was tested for the management of critical-sized defects in an ovine model. Morphology, calcium release...
Long term performance evaluation of small-diameter vascular grafts based on pol...
Alexandre, Nuno; Amorim, Irina; Caseiro, Ana Rita; Pereira, Tiago; Alvites, Rui; Rêma, Alexandra; Gonçalves, Ana; Costa, Elisio; Santos-Silva, AliceThe functional and structural performance of a 5 cm synthetic small diameter vascular graft (SDVG) produced by the copolymerization of polyvinyl alcohol hydrogel with low molecular weight dextran (PVA/Dx graft) associated to mesenchymal stem cells (MSCs)-based therapies and anticoagulant treatment with heparin, clopidogrel and warfarin was tested using the ovine model during the healing period of 24 weeks. The ...