36 documents found, page 1 of 4
Effect of Aflatoxin B1 in both Caco-2 and Caco-2/HT29-MTX models
Serrenho, I.; Vidal, N.; Rolo, D.; Louro, H.; Pereira, J.; Matos, P.; Jordan, P.; Alvito, P.About effect of Aflatoxin B1 in both Caco-2 and Caco-2/HT29-MTX models within the scope of the intestinal absorption assessment and enabling formulations.
Early-life exposure to MYCOtoxins and its impact on health – a case study
Alvito, P.; Assunção, R.; Bastos-Amador, P.; de Boevre, M.; Duarte, E.; Martins, C.; Serrenho, i.; Silva, I.; Visintin, L.; Ferreira, M.Considering the potential impact on health and the scarce data available regarding early-life exposure to mycotoxins, earlyMYCO project (early-life exposure to MYCOtoxins and its impact on health) proposed to answer key questions: are pregnant women and infants until six months exposed to mycotoxins? Is this exposure a health threat? Does this early-life exposure influence the intestinal immune system developme...
earlyMYCO – a mother & child cohort in Portugal to assess exposure to mycotoxins
Martins, C.; Assunção, R.; Serrano, D.; De Boevre, M.; De Saeger, S.; Alvito, P.; Vidigal, C.; Lamy, E.; Nunes, C.Aim: This study aims for the first time in Portugal to assess the early-life exposure to mycotoxins through a mother & child cohort.
Early-life exposure to mycotoxins: assessing the risk under the earlyMYCO project
Assunção, R.; Martins, C.; Nunes, Baltazar; Silvia, S.; Pires, S.M.; Alvito, P.Exposure to hazardous chemicals during the first 1000 days of life has been associated to a number of health disorders, e.g. non-communicable diseases. A proper risk assessment built on accurate data assumes particular importance to evaluate the potential impact that early-life exposure could represent in adulthood. Mycotoxins, secondary fungal metabolites, could have harmful effects in humans and animals. Rece...
SafeGrains - Contamination of stored grain and derivatives by insect pests and ...
Carvalho, M.O.; Mourato, M.; Louro, L.; Sousa, I.; Raymundo, A.; Alvito, P.; Magro, A.; Barros, G.; Ferreira, R.; Duarte, S.About contamination of stored grain and derivatives by insect pests and fungi.
earlyMYCO – a mother & child pilot study to assess early-life exposure to mycot...
Martins, C.; Assunção, R.; Costa, A.; Serrano, D.; Namorado, S.; Vidigal, C.; Almeida, E.; Alvito, P.; Nunes, C.Early-life exposure occurs during gestation through transfer of toxic substances present in the maternal diet to the fetus and later during lactation, through the breast milk. Mycotoxins are well known carcinogenic, nephrotoxic, hepatotoxic, and immunosuppressive food chemical contaminants. Recently, human biomonitoring data revealed that Portuguese population is exposed to mycotoxins. These results emphasized ...
earlyMYCO: assessing the risk associated to the early-life exposure to mycotoxins
Assunção, R.; Martins, C.; Nunes, B.; Namorado, S.; Silva, S.; Pires, S.M.; Alvito, P.A number of health disorders, e.g. non-communicable diseases, has been associated to exposure with hazardous chemicals during the first 1000 days of life. In this context, a proper risk assessment built on accurate data assumes particular importance to evaluate the potential impact that early-life exposure could represent in adulthood. Mycotoxins are secondary fungal metabolites that could produce harmful effec...
Exposure of gastrointestinal tract to aflatoxin B1: an overlooked impact?
Serrenho, I.; Assunção, R.; Alvito, P.Introduction: Human exposure to aflatoxin B1 (AFB1) through contaminated food ingestion and its impact on the gastrointestinal tract (GIT) is a field of scientific growing interest. Beyond the recognized carcinogenic potential, AFB1 has the ability to disrupt the intestinal barrier affecting its balance and dynamics, and could promote the development of chronic intestinal inflammation, among other pathologies. ...
Human biomonitoring of multiple mycotoxins in biological samples of Portuguese ...
Visintin, L.; García-Nicolás, M.; Dhondt, E.; Martins, C.; Assunção, R.; Serrano, D.; Alvito, P.; Vidigal, C.; Almeida, E.; Nunes, C.; De Saeger, S.Early-life exposure to hazardous compounds is an emerging research field that urgently needs to be investigated, as an attempt to contribute to exposome research. Mycotoxins are naturally-occurring food contaminants and recent studies reported that Portuguese children (< 3 years) as well as the adult population are exposed to multiple mycotoxins through food consumption constituting a potential health threat. C...
4th International Conference on Food Contaminants (ICFC) 2021: Challenges on ea...
Vasco, E.; Martins, C.; Serrenho, I.; Assunção, R.; Alvito, P.(...) Exposure to hazardous chemicals during first 1000 days of life has been linked to an increased risk of a number of health disorders.There is growing evidence that early-life exposure to chemical hazards can lead to non-communicable diseases (NCDs) in adulthood including cancer, diabetes, obesity and auto-immune diseases. Because cells are rapidly dividing and organ systems are developing during childhood ...